DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment blw and atp5f1a

DIOPT Version :9

Sequence 1:	NP_726243.1	Gene:	blw / 37617	FlyBaseID:	FBgn0011211	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_031756756.1	Gene:	atp5f1a / 594998	XenbaseID:	XB-GENE-944567	Length:	587	Species:	Xenopus tropicalis

Alignment Length:	587	Identity:	458/587 - (78%)
Similarity:	500/587 - (85%)	Gaps:	39/587 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IFSARLASSVARNLPKAANQVACKAAYPAASLAARKLHVAST--QRS--AEISNILEERILGVAP 63
            :.|.|:|:::||.||:.|..|: |.|..||.:|.|.:|.:..  |:|  ||:|:||||||||...
Frog     1 MLSVRVATALARTLPRQAGLVS-KKALGAAFVATRNIHASGAWLQKSGTAEVSSILEERILGADT 64

  Fly    64 KADLEETGRVLSIGDGIARVYGLNNIQADEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKQGD 128
            .||||||||||||||||||||||.|:||:||||||||||||:||||||||||||||||||||:||
Frog    65 SADLEETGRVLSIGDGIARVYGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGD 129

  Fly   129 IVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGAINTKDRFRVGIKAPGIIPRVSVREPMQTGIK 193
            |||||||||||||||||||||||||||||||||.:.:|.|.|||:||||||||:|||||||||||
Frog   130 IVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGPLASKIRRRVGLKAPGIIPRISVREPMQTGIK 194

  Fly   194 AVDSLVPIGRGQRELIIGDRQTGKTALAIDTIINQKRFNEAQDESKKLYCIYVAIGQKRSTVAQI 258
            |||||||||||||||||||||||||::||||||||||||:..||.|||||||||||||||||||:
Frog   195 AVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQL 259

  Fly   259 VKRLTDSGAMGYSVIVSATASDAAPLQYLAPYSGCAMGEYFRDKGKHALIIYDDLSKQAVAYRQM 323
            ||||||:.||.|:::||||||||||||||||||||:|||||||.|||||||||||||||||||||
Frog   260 VKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQM 324

  Fly   324 SLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPAMGGGSLTALPVIETQAGDVSAYIPTNVISIT 388
            |||||||||||||||||||||||||||||||:...||||||||||||||||||||||||||||||
Frog   325 SLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDHFGGGSLTALPVIETQAGDVSAYIPTNVISIT 389

  Fly   389 DGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGSMKLELAQYREVAAFAQFGSDLD 453
            ||||||||||||||||||||||||||||||||||:|||||||:||||||||||||||||||||||
Frog   390 DGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLD 454

  Fly   454 AATQQLLNRGVRLTELLKQGQY----------------------------------VPMAIEDQV 484
            ||||||||||||||||||||||                                  ||||||:||
Frog   455 AATQQLLNRGVRLTELLKQGQYGKYLLGPQRLSRLPICVSACSSRAISFHQCAFVAVPMAIEEQV 519

  Fly   485 AVIYCGVRGHLDKMDPAKITKFEKEFLQHIKTSEQALLDTIAKDGAISEASDAKLKDIVAKFMST 549
            .|||.|||||||||:|:||||||..||.|:|:..|.||.||..||.|||.:|||||:||..|:||
Frog   520 TVIYAGVRGHLDKMEPSKITKFENAFLAHVKSQHQELLATIRADGKISEQADAKLKEIVLSFLST 584

  Fly   550 FQ 551
            |:
Frog   585 FE 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blw	NP_726243.1	PRK09281	46..552	CDD:236448	441/542 (81%)
		ATP-synt_ab_N	68..134	CDD:280947	60/65 (92%)
		F1_ATPase_alpha	136..417	CDD:238552	253/280 (90%)
		ATP-synt_ab_C	426..520	CDD:278722	80/127 (63%)
atp5f1a	XP_031756756.1	PRK09281	49..587	CDD:236448	440/538 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	408	1.000	Domainoid score	I692
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2985
Inparanoid	1	1.050	881	1.000	Inparanoid score	I396
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186910at33208
OrthoFinder	1	1.000	-	-		FOG0002237
OrthoInspector	1	1.000	-	-		oto104226
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1480
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060