DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42260 and CNGC8

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_173408.2	Gene:	CNGC8 / 838566	AraportID:	AT1G19780	Length:	753	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	128/562 - (22%)
Similarity:	223/562 - (39%)	Gaps:	138/562 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   572 VFDPAGRLCYYWS--------MVVSMAFLYNFWVII----------YRFAFQEINRRTIAIWFCL 618
            :|||..:....|:        :.||:..|:.:..|:          .:.|......|||.
plant    97 IFDPQDKTLLLWNRMFVISCILAVSVDPLFFYLPIVDNSKNCIGIDSKLAVTTTTLRTII----- 156

  Fly   619 DYLSDFLYLIDILFHFRTGYLED-------GVLQTDALKLRTHYMNSTIFYIDCLCLLPL----- 671
                |..||..:...|||.|:..       |.|..|..|:...|: :..|.:|.|.:|||
plant   157 ----DVFYLTRMALQFRTAYIAPSSRVFGRGELVIDPAKIAERYL-TRYFIVDFLAVLPLPQIAV 216

  Fly   672 -DFLYLSIGFNSILRSFRLVKIY------RFWAFMDRTERHTNYPNLFRSTA-------LIHYLL 722
             .||:.|.|.:.:.....|:.|.      ||..|:..|.........|...|       |:.|:|
plant   217 WKFLHGSKGTDVLPTKQALLHIVITQYIPRFVRFIPLTSELKKTAGAFAEGAWAGAAYYLLWYML 281

  Fly   723 VIFHWNGCLYHI-----------------------------------------------IHKNN- 739
            . .|..|..:::                                               :.|||
plant   282 A-SHITGAFWYMLSVERNDTCLRSACKVQPDPKVCVQILYCGSKLMSSRETDWIKSVPDLFKNNC 345

  Fly   740 ---------GFGSRNWVYHDSESADVV------KQYLQSYYWCTLALTTIGD-LPKPRSKGEYVF 788
                     .:|    :|..:.|:.:|      .::....:|....|:|:|. |......||.:|
plant   346 SAKSDESKFNYG----IYSQAVSSGIVSSTTFFSKFCYCLWWGLQNLSTLGQGLQTSTYPGEVLF 406

  Fly   789 VILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLW 853
            .|...:.||:|||.::|::...:.|::...:|.:.|....:.:|..|.:|.:|:.:|.::..|.|
plant   407 SIAIAVAGLLLFALLIGNMQTYLQSLTVRLEEMRIKRRDSEQWMHHRSLPQNLRERVRRYDQYKW 471

  Fly   854 LTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYIC 918
            |..:..|||..|..||..|:.:|..::.|:.::||.:|.|.:...|..:..||:|.|::...||.
plant   472 LETRGVDEENIVQSLPKDLRRDIKRHLCLNLVRRVPLFANMDERLLDAICERLKPSLYTESTYIV 536

  Fly   919 RKGEVGKEMYIVNRGRLQ-VVADNGKTVMAS---LKAGSYFGEISILNMG---TAGNR---RTAS 973
            |:|:...||..:.||||: |..|.|::...:   ||.|.:.|| .:|...   .||:.   .|.:
plant   537 REGDPVNEMLFIIRGRLESVTTDGGRSGFFNRGLLKEGDFCGE-ELLTWALDPKAGSNLPSSTRT 600

  Fly   974 VRSVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRLEKY 1015
            |:::...:.|.|..:::..|..::.    ||.|..|::..::
plant   601 VKALTEVEAFALEAEELKFVASQFR----RLHSRQVQQTFRF 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	67/345 (19%)
		CAP_ED	890..1004	CDD:237999	33/123 (27%)
		DUF4655	1084..>1154	CDD:317882
CNGC8	NP_173408.2	Ion_trans	150..437	CDD:278921	61/301 (20%)
		Crp	502..>637	CDD:223736	39/139 (28%)
		CAP_ED	508..639	CDD:237999	37/136 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910