DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and CNGC16

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_190384.1	Gene:	CNGC16 / 823956	AraportID:	AT3G48010	Length:	705	Species:	Arabidopsis thaliana

Alignment Length:	588	Identity:	129/588 - (21%)
Similarity:	230/588 - (39%)	Gaps:	139/588 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   543 HGGQPHHQKPRRTASQRIRAATAARKLHFVFDPAGRLCYYWS--------MVVSMAFLYNFWVII 599
            |...|::|: ||:...::|..|        .||.|.|...|:        :.:.:..||.:..|:
plant    24 HHNDPNNQR-RRSIFSKLRDKT--------LDPGGDLITRWNHIFLITCLLALFLDPLYFYLPIV 79

  Fly   600 YR-FAFQEINRRTIAIWFCLDYLSDFLYLIDILFHFRTGYLED-------GVLQTDALKLRTHYM 656
            .. .|...|:.|......|...|:|..:||.||..|:|.::..       |.|..|..::...|:
plant    80 QAGTACMSIDVRFGIFVTCFRNLADLSFLIHILLKFKTAFVSKSSRVFGRGELVMDRREIAIRYL 144

  Fly   657 NSTIFYIDCLCLLPL-------------DFLYLSIGFNSILRSFRLVKIYRFWAFMDRTERHTNY 708
            .|. |.||....|||             :|.|.:...:::.....:..:.||...:....|....
plant   145 KSE-FVIDLAATLPLPQIMIWFVIPNAGEFRYAAHQNHTLSLIVLIQYVPRFLVMLPLNRRIIKA 208

  Fly   709 PNLFRSTA-------LIHYLLVIFHWNGCLYHI--------------IHKNNGF----------- 741
            ..:...||       ||.|||| .|..|.::::              |.:.|..
plant   209 TGVAAKTAWSGAAYNLILYLLV-SHVLGSVWYVLSIQRQHECWRRECIKEMNATHSPSCSLLFLD 272

  Fly   742 -------GSRNW-----------------------VYHDSESADVVKQ-YLQSYYWC-------- 767
                   |.:.|                       ::.|:.:.||... :...|::|
plant   273 CGSLHDPGRQAWMRITRVLSNCDARNDDDQHFQFGMFGDAFTNDVTSSPFFDKYFYCLWWGLRNL 337

  Fly   768 -----TLALTTIGDLPKPRSKGEYVFVILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDG 827
                 :||.:|:        ..|.:|.....:.||:.|:.::|:|.|.:.|.:|...|::.:...
plant   338 SSYGQSLAASTL--------SSETIFSCFICVAGLVFFSHLIGNVQNYLQSTTARLDEWRVRRRD 394

  Fly   828 VKTYMRMRRVPNHLQVKVIKWFDYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQ 892
            .:.:||.|::|:.||.:|.::..|.|||.:..|||..:..||..|:.:|..::.|..::||..|.
plant   395 TEEWMRHRQLPDELQERVRRFVQYKWLTTRGVDEEAILRALPLDLRRQIQRHLCLALVRRVPFFA 459

  Fly   893 NTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYIVNRGRLQ-VVADNGKTVM---ASLKAGS 953
            ..:...|..:..||.|.|.:...|:.|:|:...||..:.||::: ...|.|::..   .:|:.|.
plant   460 QMDDQLLDAICERLVPSLNTKDTYVIREGDPVNEMLFIIRGQMESSTTDGGRSGFFNSITLRPGD 524

  Fly   954 YFGEISILNMGTAGN------RRTASVRSVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRL 1012
            :.|| .:|......|      ..|.:||::...:.|.|..:|:..|..::.    ||.|..::..
plant   525 FCGE-ELLTWALVPNINHNLPLSTRTVRTLSEVEAFALRAEDLKFVANQFR----RLHSKKLQHA 584

  Fly  1013 EKY 1015
            .:|
plant   585 FRY 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	64/342 (19%)
		CAP_ED	890..1004	CDD:237999	28/123 (23%)
		DUF4655	1084..>1154	CDD:317882
CNGC16	NP_190384.1	Ion_trans	94..386	CDD:278921	57/301 (19%)
		Crp	451..>586	CDD:223736	33/139 (24%)
		CAP_ED	457..588	CDD:237999	32/136 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910