DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42260 and CNGC12

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_001324486.1	Gene:	CNGC12 / 819253	AraportID:	AT2G46450	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	122/538 - (22%)
Similarity:	212/538 - (39%)	Gaps:	132/538 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   553 RRTASQRIRAATAARKLHFVFDPAGRL---------CYYWSMVVSMA----------FLYNFWVI 598
            ||:...||.:.....||..|   .|||         ...|...|.:|          ||:...:.
plant     4 RRSKFARIDSMGVDGKLKSV---RGRLKKVYGKMKTLENWRKTVLLACVVALAIDPLFLFIPLID 65

  Fly   599 IYRFAFQEINRRTIAIWFCLDYLSDFLYLIDILFHFRT--------GYLEDGVLQTDALKLRTHY 655
            ..||.| ..::..:|:...:....|..|:|.|:::..|        ..|...::......|:|..
plant    66 SQRFCF-TFDKTLVAVVCVIRTFIDTFYVIHIIYYLITETIAPRSQASLRGEIVVHSKATLKTRL 129

  Fly   656 MNSTIFYIDCLCLLP------LDFLYLSIGFNS-------ILRSF--RLVKIYRFWAFMDR---T 702
            :..  |.:|.:.:||      |..:.||....|       ||..:  |::::|..:..:.|   |
plant   130 LFH--FIVDIISVLPIPQVVVLTLIPLSASLVSERILKWIILSQYVPRIIRMYPLYKEVTRAFGT 192

  Fly   703 ERHTNYP----NLFRSTALIH--------YLLVIFHWNGC--------------LYHIIHKNNG- 740
            ...:.:.    |||  ..::|        ||..|...:.|              :..::.|..|
plant   193 VAESKWAGAALNLF--LYMLHSYVFGAFWYLSSIERKSKCWRAACARTSDCNLTVTDLLCKRAGS 255

  Fly   741 -------------------------FGSRNWVYHDS--------ESADVVKQYLQSYYWCTLALT 772
                                     ||    :|.|:        :..|..::::..::|....::
plant   256 DNIRFLNTSCPLIDPAQITNSTDFDFG----MYIDALKSGVLEVKPKDFPRKFVYCFWWGLRNIS 316

  Fly   773 TIG-DLPKPRSKGEYVFVILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRR 836
            .:| :|....|.||..|.|:..:.||:|||.::|:|...:.|.:....|.:.|....:.:|..|.
plant   317 ALGQNLETSNSAGEIFFAIIICVSGLLLFAVLIGNVQKYLQSSTTRVDEMEEKRRDTEKWMSYRV 381

  Fly   837 VPNHLQVKVIKWFDYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCE 901
            :|.:|:.::.::.||.|...|.::||..:..||..|:.|....::||.||||......:.|:|.|
plant   382 IPEYLKERIRRFEDYKWRETKGTEEEALLRSLPKDLRLETKRYLYLDMLKRVPWLNIMDDGWLLE 446

  Fly   902 LVL-RLRPVLFSPGDYICRKGEVGKEMYIVNRGRLQVVADNGKTVM------ASLKAGSYFGEIS 959
            .|. |::.|.:....:|.|:|...:||.||.||:|:  :..|...|      ..|:.|...||:
plant   447 AVCDRVKSVFYLANSFIVREGHPVEEMLIVTRGKLK--STTGSHEMGVRNNCCDLQDGDICGEL- 508

  Fly   960 ILNMGTAGNRRTASVRSV 977
            :.|    |:|...|.|:|
plant   509 LFN----GSRLPTSTRTV 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	62/334 (19%)
		CAP_ED	890..1004	CDD:237999	28/95 (29%)
		DUF4655	1084..>1154	CDD:317882
CNGC12	NP_001324486.1	Ion_trans	<302..362	CDD:395416	16/59 (27%)
CNGC12	NP_001324486.1	CAP_ED	435..560	CDD:237999	28/95 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920