DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42260 and CNGC6

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_001323881.1	Gene:	CNGC6 / 816931	AraportID:	AT2G23980	Length:	770	Species:	Arabidopsis thaliana

Alignment Length:	585	Identity:	140/585 - (23%)
Similarity:	228/585 - (38%)	Gaps:	132/585 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   522 GHPHHPHHGGAGSGGGSGPGSHGGQPHHQKPRRTASQRIRAATAARKLHF----VFDPAGR---L 579
            |.|.....|...|.|....|...|........|:....:..|.....|..    :|||..:   |
plant    49 GGPKRFAQGSKASSGSFKKGFRKGSEGLWSIGRSIGLGVSRAVFPEDLEVSEKKIFDPQDKFLLL 113

  Fly   580 C---YYWSMVVSMA----FLYNFWVIIYRFAFQEINRRTIAIWFCLDYLSDFLYLIDILFHFRTG 637
            |   :..|.:::::    ||| ...|..:.....|:|:...|...:..:.|..||..:...|||.
plant   114 CNKLFVASCILAVSVDPLFLY-LPFINDKAKCVGIDRKLAIIVTTIRTVIDSFYLFHMALRFRTA 177

  Fly   638 YLED-------GVLQTDALKLRTHYMNSTIFYIDCLCLLPLD------FLYLSIGFNSI-----L 684
            |:..       |.|..|..::...|:.. .|.||.|.:||:.      |||.|.|.|.:     |
plant   178 YVAPSSRVFGRGELVIDPAQIAKRYLQQ-YFIIDLLSVLPVPQIIVWRFLYTSRGANVLATKQAL 241

  Fly   685 RSFRLVK-IYRF---------------------WA------FMDRTERHTN--------YPNL-- 711
            |...||: |.||                     ||      .:.....|.:        ||.|
plant   242 RYIVLVQYIPRFLRMYPLSSELKRTAGVFAETAWAGAAYYLLLYMLASHVSIQFSCTILYPFLCS 306

  Fly   712 -----FRSTALIHYLLVIFHWNGCLYHIIHKNNG-------FGSRN------W------------ 746
                 .:....:.|||.:...|.|.....|.|..       .|::|      |
plant   307 HKFMCMQIVGALWYLLALERNNDCWSKACHNNQNCTRNFLFCGNQNMKGYAAWDNIKVSYLQLKC 371

  Fly   747 ---------------VYHDSESADVV--KQYLQSYYWC----TLALTTIGD-LPKPRSKGEYVFV 789
                           :|..:.|:.:|  |.::..|::|    ...|:|:|. |......||.:|.
plant   372 PVNVPEDEEPPFDFGIYLRALSSGIVSSKNFVSKYFFCLWWGLQNLSTLGQGLETSTYPGEVIFS 436

  Fly   790 ILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWL 854
            |...:.||:|||.::|::...:.|::...:|.:.|....:.:|..|.:|..|:.:|.::..|.||
plant   437 ITLAIAGLLLFALLIGNMQTYLQSLTIRLEEMRVKRRDSEQWMHHRMLPPELRERVRRYDQYKWL 501

  Fly   855 TQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICR 919
            ..:..|||..|..||..|:.:|..::.|..::||.:|:|.:...|..:..||:|.||:...|:.|
plant   502 ETRGVDEENLVQNLPKDLRRDIKRHLCLALVRRVPLFENMDERLLDAICERLKPCLFTEKSYLVR 566

  Fly   920 KGEVGKEMYIVNRGRLQ-VVADNGKTVM---ASLKAGSYFGEISILNMG---TAGNRRTASVRSV 977
            :|:...||..:.||||: |..|.|::..   :.||.|.:.|: .:|...   .:|:...:|.|:|
plant   567 EGDPVNEMLFIIRGRLESVTTDGGRSGFYNRSLLKEGDFCGD-ELLTWALDPKSGSNLPSSTRTV 630

Fly 978 977
plant 631 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	75/349 (21%)
		CAP_ED	890..1004	CDD:237999	29/95 (31%)
		DUF4655	1084..>1154	CDD:317882
CNGC6	NP_001323881.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910