DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and LOC562466

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	XP_009295831.2	Gene:	LOC562466 / 562466	-ID:	-	Length:	801	Species:	Danio rerio

Alignment Length:	551	Identity:	172/551 - (31%)
Similarity:	290/551 - (52%)	Gaps:	45/551 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   545 GQPHHQKPRRTASQRIRAATAARKLHFV--------------------FDP-AGRLCYYWSMVVS 588
            |:|..:|..:|..::    :...|::|.                    .|| ..|....|..:|:
Zfish   263 GKPVEKKDDKTDEKK----SIFSKVNFTCVDFVLKPFEMRMDNRIGKSIDPFTDRRYITWLSMVT 323

  Fly   589 MAFLYNFWVIIYRFAFQEINRRTIAIWFCLDYLSDFLYLID-ILFHFRTGYLEDGVLQTDALKLR 652
            :||.||.|.:..|.||...:...:.:||.||.::||:|:.| |.|..|..:.:.|.:..|...::
Zfish   324 IAFNYNLWFVPVRMAFPYHSPEVVPLWFTLDIIADFIYIFDMIFFQPRLQFSKGGDIIYDREVIK 388

  Fly   653 THYMNSTIFYIDCLCLLPLDFLYLSIGFNSILRSFRLVKIYRFWAFMDRTERHTNYPNLFRSTAL 717
            ..|..|..|..|.:.:||:|.||:..||||:.|..||:|:..|:.|.||.|.......::|....
Zfish   389 KKYRESGRFQNDVIAVLPIDLLYIPFGFNSVFRLNRLMKVESFFEFSDRLEGLLTRAYIWRVIRT 453

  Fly   718 IHYLLVIFHWNGCLYHIIHKNNGFGSRNWVYHDSESADVVKQYLQSYYWCTLALTTIGDLPKPRS 782
            |.|||.|.|.|.|||::...:.|.||..|||....||     ||..:::...:|..|.:||.|.:
Zfish   454 IGYLLFILHLNACLYYVASVSQGIGSTKWVYSGKGSA-----YLSCFFYAEKSLLMIAELPFPET 513

  Fly   783 KGEYVFVILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIK 847
            ....:|.:.....|.:..:.:|..:.:::.:.:|.:..|:|.:|....||....:|..:|.:|..
Zfish   514 MFGQIFQMTNYFVGALFLSIILAQMRDVIGAATAGQTYFRASMDACVAYMVTNHIPKMVQSRVRT 578

  Fly   848 WFDYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFS 912
            |::|.|.:|...||...:..:|..::..||::::|.|.:::|:|:..:...|.:::|||:.:::.
Zfish   579 WYNYTWDSQGMLDESELLGQMPLVMRTAIAVDINLATFQKIELFKGCDNQMLVDMLLRLKSIVYL 643

  Fly   913 PGDYICRKGEVGKEMYIVNRGRLQVVA--DNGKTVMASLKAGSYFGEISIL-NMGTAGNRRTASV 974
            |||::.:||::||||||:..|.:||:.  || |.|..:||||..|||||:| :....||||||:|
Zfish   644 PGDFVVKKGDIGKEMYIIKAGEVQVIGGPDN-KIVFVTLKAGCVFGEISLLQSSANGGNRRTANV 707

  Fly   975 RSVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRLEKYK------KAPLEKVKYFNVVAMGR 1033
            .:.|:::||||.|||:.|:|..||.:: ::.:...::|.|.|      ||..||.|  .:...|:
Zfish   708 AAHGFANLFVLDKKDLNDILIHYPESQ-KVLARKGRKLLKAKGPPPAAKADEEKKK--GLALFGQ 769

  Fly  1034 CQSTPGLVES-CGRTSLEEMWLPPATAGASS 1063
            ...||.::.: .|.|..::.:|......||:
Zfish   770 KPPTPKMLRAFAGGTFTKKGFLDRLKNAASN 800

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	75/238 (32%)
		CAP_ED	890..1004	CDD:237999	52/116 (45%)
		DUF4655	1084..>1154	CDD:317882
LOC562466	XP_009295831.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920