DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and sei

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_001286814.1	Gene:	sei / 37843	FlyBaseID:	FBgn0003353	Length:	855	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	115/507 - (22%)
Similarity:	221/507 - (43%)	Gaps:	73/507 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   583 WSMVVSMAFLYNFWVIIYRFAF----QEINRRT--------IAIWFCLDYLSDFLYLIDILFHFR 635
            |..::.:..:|......|..||    |:..||.        |.|   :|.:.|..:::||:.:||
  Fly   323 WDWIILILVMYTAIFTPYVAAFLLGEQDYQRRNSKYINSDPIVI---IDLIVDVTFIVDIIINFR 384

  Fly   636 TGYL--EDGVLQTDALKLRTHYMNSTIFYIDCLCLLPLDFLYLS---------IGFNSILRSFRL 689
            |.::  :|.|:.... ::..||: |..|.||.:..:|.|.|.:.         ||.....|..||
  Fly   385 TTFVNSQDEVVSHPG-RIAVHYL-SGWFLIDLVAAVPFDLLLVGSDTDETTTLIGLLKTARLLRL 447

  Fly   690 VKIYRFWAFMDRTERHTNYPNLFRSTALIHYLLVIF----HWNGCLYHII-HKNNGFGSRN--WV 747
            |::.|      :.:|::.|     ..|::..|:..|    ||..|:::.| :......|:|  |:
  Fly   448 VRVAR------KIDRYSEY-----GAAVLILLMATFILIAHWLACIWYAIGNAEKSIASKNIGWL 501

  Fly   748 ----------YHDSESA--DVVKQYLQSYYWCTLALTTIG-DLPKPRSKGEYVFVILQLLFGLML 799
                      |.|:.:.  .:..:|:.:.|:...:||::| ....|.:..|..|.|..:|.|.::
  Fly   502 NSLAYDIQEPYFDNRTGGPSIKSRYITALYFTFTSLTSVGFGNVAPNTDAEKAFTICVMLVGSLM 566

  Fly   800 FATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQKCSDEERA 864
            :|::.|:|:.|:..:.:....:..::..|:.::|..::||.|:.::.::|.:.|......|....
  Fly   567 YASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNSL 631

  Fly   865 VSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYI 929
            :...|:.|:|:|.::::...|.....|.....|.|....|:.:.....|||.:..:|:|...:|.
  Fly   632 LKGFPECLQADICLHLNRKLLTTCAAFSEASPGCLRAFSLKFKTTHAPPGDILVHRGDVLTSLYF 696

  Fly   930 VNRGRLQVVADNGKTVMASLKAGSYFGEISILNMGTAGNRRTASVRSVGYSDLFVLSKKDMWDVL 994
            :.||.:::.......|:..   ...|||...: ..|.| :....||::.|.|:..|.:.|:.|||
  Fly   697 IARGSIEIQRAGNIVVLGK---NDIFGENPCI-YPTVG-KSNGVVRALTYCDIHKLHRDDLLDVL 756

  Fly   995 KEYPAARVRLESIAVKRLEKYKKAPLE------KVKYFNVVAMGRCQSTPGL 1040
            ..||..   |||.....:..|.....|      |.:|....:..:.:|:|.:
  Fly   757 DSYPEF---LESFVSNLVITYNMRDDEHSGVDIKHRYLRAKSSDKMRSSPDI 805

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	64/278 (23%)
		CAP_ED	890..1004	CDD:237999	29/113 (26%)
		DUF4655	1084..>1154	CDD:317882
sei	NP_001286814.1	Ion_trans	360..583	CDD:278921	56/238 (24%)
		Ion_trans_2	<526..580	CDD:285168	15/53 (28%)
		CAP_ED	657..767	CDD:237999	32/117 (27%)
		Crp	666..>766	CDD:223736	29/107 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910