Protein Alignment CG42260 and CngA

DIOPT Version :9

• Sequence 1: NP_001356969.1
• Gene: CG42260 / 37614
• FlyBaseID: FBgn0259145
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Alignment Length: 905
• Identity: 287/905 - (31%)
• Similarity: 417/905 - (46%)
• Gaps: 204/905 - (22%)

  Fly   359 PKFGQSVSQQGFF----------TSHDSLATPCASRASNSHMATVSTA----------------- 396
            ||:|.::|.:..:          ::...|..||     .||.||:..|
  Fly    29 PKYGYNLSNRPMYRTTRLVGPASSAPAQLQLPC-----GSHQATLGVAPPPLEEISGGLFAPFAP 88

  Fly   397 ------------------SEMDLLHNKQRNKSRGRLKTAASGDQPLLGTWNRSTGRGSQDNTLAG 443
                              .|:..||..:|                   :|.|...:|.  :...|
  Fly    89 TATITVEQAATSIPMAVDGEVHHLHYPRR-------------------SWQRKYRQGI--HRQPG 132

  Fly   444 GGA----------TSLAMGGHNQYGGNYCNGTDRYPRSRSQQQGHHNAAQQAHHPYQLQHSASTV 498
            |||          ..:.....:::|.:.|........:|:.    |:..|:.|:......|:...
  Fly   133 GGAEQDEDEEEDDDDVDEDDDDEFGASVCEDNPEEAIARAD----HDTQQKQHYQPNASDSSYVE 193

  Fly   499 SHHPHAHGPPSQGGPGG-----------------PGPPHGGHPHHPHHGGAGSGGGSGPGSHGGQ 546
            :.......|..:..|..                 |.||........:.......|...|.....
  Fly   194 NGRKLIQEPSKRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDA- 257

  Fly   547 PHHQKPRRTASQRIRAATA-ARKLHFVFDPAGRLCYYWSMVVSMAFLYNFWVIIYRFAFQEINRR 610
                    ..|..||.::. ..:|.  .||..:..|.|..:||:|.|||...::.|..|.|||:.
  Fly   258 --------ALSSEIRGSSVLCNRLS--VDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKS 312

  Fly   611 TIAIWFCLDYLSDFLYLIDILFHFRTGYLEDGVLQTDALKLRTHYMNSTIFYIDCLCLLPLDFLY 675
            ..|.|:.||||.||:||:|.|.|...|:|:.|:|..||.:||.||.::..:|:|.|.:||.|..|
  Fly   313 APAFWYTLDYLCDFIYLLDTLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAY 377

  Fly   676 ----------LSIGFNSILRSFRLVKIYRFWAFMDRTERHTNYPNLFRSTALIHYLLVIFHWNGC 730
                      |.:....|:|..||::|.|.|.:.||||..|.|||.||...::..:||:.|||.|
  Fly   378 IWWPPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNAC 442

  Fly   731 LYHIIHKNNGFGSRNWVY--HDSESADVVKQYLQSYYWCTLALTTIGDLPKPRSKGEYVFVILQL 793
            :|..|....||.|.:|||  :.:.:..:.:||:.|:||.||.|||||:.|.|.:..||:||:...
  Fly   443 MYFAISYEIGFSSDSWVYNLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADF 507

  Fly   794 LFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQKC 858
            |.|:::|||::|::.:::::::.||.|||.::||||.||..|||.:.|:.:||:||.|.|.....
  Fly   508 LAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGA 572

  Fly   859 SDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEV 923
            .||||.::.|||||||||||.||:||||:|.||.:||.|.|..|||:|:..:|||||||||||:|
  Fly   573 LDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDV 637

  Fly   924 GKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNM--GTAGNRRTASVRSVGYSDLFVLS 986
            |||||||.||:|.||.|:|.||:|:|.|||.|||:|:|.:  ...||||||:|||:||||||.|:
  Fly   638 GKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLA 702

  Fly   987 KKDMWDVLKEYPAARVRLESIAVKRLEKYKKAPLEKVKYFNVVAMGRCQSTPGLVESCGRTSLEE 1051
            |:|:|:.|.:||.||                         :.:....||
  Fly   703 KRDLWETLSDYPEAR-------------------------STLTQRGCQ---------------- 726

  Fly  1052 MWLPPATAGASSLMHHHQALQQQHQASQQQPHRQESTQTSSQTHGYSPRSYADRLARA----TDS 1112
                        |:.....|.:|..|..|:.|  :|.:...:....|..:...||||.    |.|
  Fly   727 ------------LLRKDGLLDEQIFADSQRVH--DSIEGGIEKLELSVENLNMRLARLLAEYTAS 777

  Fly  1113 PRSV-----------SPSAHGSEERPRSRTTSH--HSI----RPQSQPSHTGHICDSSSQ 1155
            ...:           .|.....|..|:||..|.  :|:    ||:|:|..|....|::.|
  Fly   778 QAKIKQRLAKLEMNGGPGTWRLECEPQSRARSGRLYSLQPKRRPRSRPDATAKSSDAAKQ 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	100/249 (40%)
		CAP_ED	890..1004	CDD:237999	72/115 (63%)
		DUF4655	1084..>1154	CDD:317882	21/90 (23%)
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	88/219 (40%)
		Ion_trans_2	<477..527	CDD:285168	22/49 (45%)
		Crp	598..>722	CDD:223736	76/148 (51%)
		CAP_ED	604..717	CDD:237999	70/112 (63%)
		CLZ	720..791	CDD:293134	16/100 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	1	0.900	-	-		E1_KOG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	1	0.900	-	-		OOG6_100817
Panther	1	1.100	-	-	P	PTHR45638
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.820