DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and Pkg21D

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	79/397 - (19%)
Similarity:	143/397 - (36%)	Gaps:	129/397 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   754 ADVVKQYLQSYYWCTLALTTIGDLPKPRSKGEYVFVILQLLFGLMLFATVLGHVANIVTSVSAAR 818
            |..|::.:.|.|            .|..:.||  |||.:...|..|:.:..|..|     |....
  Fly   191 ASQVRELVDSMY------------SKSIAAGE--FVIREGEVGAHLYVSAAGEFA-----VMQQG 236

  Fly   819 KEFQAKLDGVKTYMRMRRVPN---HLQVKVIKWFDYLWLTQK--------CSDEERAVSCLPDKL 872
            |... |:...|.:..:..:.|   ...::|:.....:|:..:        |:..:|
  Fly   237 KVLD-KMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVFQQIMMCTGLQR--------- 291

  Fly   873 KAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYIVNRGRLQV 937
             .|.::|.    |:.|.:..|.....|.::...|....::.|.||.|:|..|...:::::|.::|
  Fly   292 -IENSVNF----LRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRV 351

  Fly   938 V-----ADNGKTVMASLKAGSYFGEISILNMGTAGNRRTASV------------------RSVGY 979
            .     ....:|.:.:|..|.||||.:::|    .::|||::                  |.:|
  Fly   352 TQKLTPTSPEETELRTLSRGDYFGEQALIN----EDKRTANIIALSPGVECLTLDRDSFKRLIG- 411

  Fly   980 SDLFVLSKKDMWDVLKEYPAARVRLESIAVKRL-EKYKKAPLEKVKYFNVVAMGRCQSTPGLVES 1043
             ||..|.:||..|..::          :|:|:. |..:..|.|:::          |..|.|
  Fly   412 -DLCELKEKDYGDESRK----------LAMKQAQESCRDEPKEQLQ----------QEFPDL--- 452

  Fly  1044 CGRTSLEEMWLPPATAGASS------LMHHHQ---------ALQQQHQASQQQPHRQESTQTSSQ 1093
             ..|.||.:    :|.|...      :..|||         .|:::|           ...|..:
  Fly   453 -KLTDLEVV----STLGIGGFGRVELVKAHHQDRVDIFALKCLKKRH-----------IVDTKQE 501

  Fly  1094 THGYSPR 1100
            .|.:|.|
  Fly   502 EHIFSER 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	15/64 (23%)
		CAP_ED	890..1004	CDD:237999	30/136 (22%)
		DUF4655	1084..>1154	CDD:317882	4/17 (24%)
Pkg21D	NP_477213.1	Crp	183..386	CDD:223736	46/232 (20%)
		CAP_ED	185..285	CDD:237999	21/113 (19%)
		CAP_ED	304..419	CDD:237999	27/120 (23%)
		Pkinase	457..717	CDD:278497	13/67 (19%)
		STKc_cGK	463..724	CDD:270724	10/57 (18%)
		S_TK_X	719..>760	CDD:214529
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910