Protein Alignment CG42260 and Cngl

DIOPT Version :9

• Sequence 1: NP_001356969.1
• Gene: CG42260 / 37614
• FlyBaseID: FBgn0259145
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: NP_001245691.1
• Gene: Cngl / 32468
• FlyBaseID: FBgn0263257
• Length: 1970
• Species: Drosophila melanogaster
• Alignment Length: 1081
• Identity: 309/1081 - (28%)
• Similarity: 456/1081 - (42%)
• Gaps: 319/1081 - (29%)

  Fly   227 YRDHSSRSINPLTA-YEQQMAELDGSFYASNAGYLGAGMGGSAGDGTTCTNLTVGGG-------- 282
            ||.|:|.....|:: |..|:          |.|..||....|:..|.|.|.|.....
  Fly     8 YRAHASAHKKILSSGYHSQL----------NYGSTGAAAASSSSSGATATGLYTMEAHEHEAGKF 62

  Fly   283 ------------------STGGGAMASGGGGTSAQVGGGGGGSGGGGAAIHTTELSITPTMAGDE 329
                              |..|.:::.||||     ||.||..|.|||..|
  Fly    63 VKDVARQVHDCNSDTDVISPTGTSISGGGGG-----GGAGGAGGSGGAGGH-------------- 108

  Fly   330 QFIDLGSLRRFSIDRQSFLDLGPKFGMTQPKFGQSVSQQGFFTSHDSLATPCASRASNSHMATVS 394
                                                |..|:...|.....    |..:::.|..|
  Fly   109 ------------------------------------SDGGYHKRHHHKMV----RDDDNNSAAHS 133

  Fly   395 TASEMDLLHNKQRNKSRGRLKTAASGDQPLLGTWNRSTGRGSQDNTLAGGGATSLAMGGHNQYGG 459
            :.|       |..::.:.|:...||...   ..|.||                       ||
  Fly   134 SDS-------KSPSQRKSRIGDGASDPD---SDWTRS-----------------------NQ--- 162

  Fly   460 NYCNGTDRYPRSRSQQQGHHNAAQQAHHPYQLQHSASTVSHHPHAHGPPSQGGPGGPGPPHGGHP 524
                   |:.:.|:..|  .::|.|...|  |:...|.:........|.:|
  Fly   163 -------RWMKLRTTVQ--ISSAIQKKPP--LKREDSFLKRFSTRQIPETQ-------------- 202

  Fly   525 HHPHHGGAGSGGGSGPGSHGGQPHHQKPRRTASQRIRAATAARKLHFVFDPAGRLCYYWSMVVSM 589
            ......|:.|..|....|       .|.||...|:.|:         |.:|.....:||.|::::
  Fly   203 ETVEDTGSESASGDVDKS-------VKRRRRYLQKRRS---------VVNPDENFYFYWLMMLTV 251

  Fly   590 AFLYNFWVIIYRFAFQEINRRTIAIWFCLDYLSDFLYLIDILFHFRTGYLEDGVLQTDALKLRTH 654
            ..|||.|.:|.|.:|.|:.:.....|...|.::|.::::||:...||||||.|::..|..||..|
  Fly   252 CVLYNLWTLIVRQSFPELQQSVPTFWLICDSMTDVVFILDIIVQLRTGYLEQGLMVYDDRKLACH 316

  Fly   655 YMNSTIFYIDCLCLLPLDFLYLSIGFNSILRSFRLVKIYRFWAFMDRTERHTNYPNLFRSTALIH 719
            |::|..|..|.:.|:|||.|.|.:|.:.:||..|..|:||...|....|..|.:|||:|...|||
  Fly   317 YVHSRDFIFDMIALIPLDLLQLKMGTHPLLRFTRFFKVYRSVRFYYIVESRTVWPNLWRVVNLIH 381

  Fly   720 YLLVIFHWNGCLYHIIHKNNGFGSRNWV--YHDSESADVVKQYLQSYYWCTLALTTIGDLPKPRS 782
            .||::.||.||.|.::.:..|| ..:||  |...:.|.:.::||.|.||.||.||||||||.|.:
  Fly   382 ILLILAHWFGCFYFLLSEAEGF-QGDWVYPYRPGDYATLTRKYLGSLYWSTLTLTTIGDLPTPET 445

  Fly   783 KGEYVFVILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIK 847
            ..||:|.|:..|.|:.:|||::|.|.|::|:.:|.|.||:..|||.|||||..:||..::.:|::
  Fly   446 NAEYIFTIVSYLIGVFIFATIVGQVGNVITNRNANRLEFERLLDGAKTYMRHHKVPGGMKRRVLR 510

  Fly   848 WFDYLW---LTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPV 909
            |:||.|   ..|...|...|:..||||||.|:|::|:|..||:|.|||..:..||.:|||:::..
  Fly   511 WYDYSWSRGRIQGGGDINTALGLLPDKLKTELALHVNLSVLKKVTIFQECQPEFLHDLVLKMKAY 575

  Fly   910 LFSPGDYICRKGEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNMGTAGNRRTASV 974
            :|:|||.|||||||.:||:|:..|.|:|:::.|| |:.::|||.:||||.|||:... |:|||.|
  Fly   576 IFTPGDSICRKGEVAREMFIIADGILEVLSETGK-VLTTMKAGDFFGEIGILNLDGL-NKRTADV 638

  Fly   975 RSVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRL-------EKYKKAPLEKVKYFNVVAMG 1032
            ||||||:||.||::|:...:|:||.|:..|:::..|||       :||.||..:|
  Fly   639 RSVGYSELFSLSREDVLAAMKDYPDAQEILQTLGRKRLMEVRCVNKKYAKAQSDK---------- 693

  Fly  1033 RCQSTPGLVESCGRTSLEEMWLPPATAGASSLMHHHQALQQQHQASQQQPHRQESTQTS------ 1091
                                   .|.|.|::..||||:   .||.   |.|:.:|::.|
  Fly   694 -----------------------EAAAYAAAHPHHHQS---HHQG---QVHQSDSSENSASKKIV 729

  Fly  1092 ----------------SQT-------------HGYSPRSY----------------ADRLARATD 1111
                            |:|             |..|||..                ||. |.|.|
  Fly   730 DKLKHDVKGFRNVLKKSRTSRKSDESLEMQPLHNTSPRGSKILLKRMSRVRSDEKDADS-AEAKD 793

  Fly  1112 SPRSVSPSAHGS-----------EERPRSRTTSHHSIRPQSQPSHTGHICDSSSQLECYGAGVGG 1165
            .....:||..|:           :|:......:..|..||..|.|:...|..|.|
  Fly   794 ELHDKTPSPIGAGLPLLQRLRLLKEKQDREERAVKSTPPQKSPPHSHVTCTLSPQ---------- 848

  Fly  1166 AGGGTTPLLGSHEVLEDEIKR-------LRERLHTVESENQ 1199
                        |.:::|.:|       |.:||..::.:|:
  Fly   849 ------------ESIQEEPEREFSEGFPLIQRLQQLKIKNE 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	97/239 (41%)
		CAP_ED	890..1004	CDD:237999	58/113 (51%)
		DUF4655	1084..>1154	CDD:317882	23/131 (18%)
Cngl	NP_001245691.1	Ion_trans	260..481	CDD:278921	90/221 (41%)
		Ion_trans_2	382..476	CDD:285168	41/94 (44%)
		Crp	550..>680	CDD:223736	65/131 (50%)
		CAP_ED	556..668	CDD:237999	58/113 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	1	0.900	-	-		E1_KOG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3583
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	1	1.000	-	-		otm2706
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45638
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970