DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and AgaP_AGAP010000

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	XP_319144.3	Gene:	AgaP_AGAP010000 / 1279427	VectorBaseID:	AGAP010000	Length:	219	Species:	Anopheles gambiae

Alignment Length:	216	Identity:	53/216 - (24%)
Similarity:	98/216 - (45%)	Gaps:	20/216 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   828 VKTYMRMRRVPNHLQVKVIKWFDYLWLTQKC-SDEERAVSCLPDKLKAEIAINVHLDTLKRVEIF 891
            ::||:|.::: :...:|....:.|....:.| ..|:..:..|.:.||..|......:.||.|:||
Mosquito    12 LQTYVRTKQL-HTADMKQRLLYYYAKRYEHCFFQEDIIMESLSESLKKRITDYSATNFLKTVKIF 75

  Fly   892 QNTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFG 956
            .......|..||.|:...::...|.|.:.|..|.:||.:..|.:.|...:.|.: ..|..|..||
Mosquito    76 DGIPNDLLLPLVERMTKEIYLQDDLIIKAGSFGDKMYFIIVGMVAVYTHSRKEI-CHLSDGDNFG 139

  Fly   957 EISILNMGTAGNRRTASVRSVGYSDLFVLSKKDMWDVLKEYPAARV---RLESIAVKRL------ 1012
            |:|:...    .:|..||.:|.::.::|:.:....::   :||..|   ||:.:|.||:
Mosquito   140 EVSMFTR----KKRLVSVVAVEFTQVYVIDRMAFKNL---FPADHVVYQRLQEMANKRMQITLVF 197

  Fly  1013 -EKYKKAPLEKVKYFNVVAMG 1032
             |::|...|:.....|.:.:|
Mosquito   198 EEQHKNYLLKMGMSQNEIKIG 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124
		CAP_ED	890..1004	CDD:237999	29/116 (25%)
		DUF4655	1084..>1154	CDD:317882
AgaP_AGAP010000	XP_319144.3	Crp	68..>195	CDD:223736	37/134 (28%)
AgaP_AGAP010000	XP_319144.3	CAP_ED	74..173	CDD:237999	26/106 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910