DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and AgaP_AGAP009798

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	XP_318891.4	Gene:	AgaP_AGAP009798 / 1279209	VectorBaseID:	AGAP009798	Length:	959	Species:	Anopheles gambiae

Alignment Length:	239	Identity:	57/239 - (23%)
Similarity:	104/239 - (43%)	Gaps:	33/239 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   811 VTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQ-KCSDEERAVSCLPDKLKA 874
            |:|..:..:|..:|:..:|...:...|.:...:|..|  |.:..|. |..|.|..:       |.
Mosquito   330 VSSQRSLIEELDSKIGTLKKTRKQGVVSDKTDLKESK--DIVIPTHPKSPDTELLI-------KT 385

  Fly   875 EIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYIVNRGRLQVVA 939
            .|..|..|:.:...|..|...|.        :..:.|.|..||.::|::|...::...|..:||.
Mosquito   386 AIVANDFLNNMMDEERLQAVTAA--------MSSMTFPPNSYIIKEGDIGAHFFVSEEGTYEVVV 442

  Fly   940 DNGKTVMASLKAGSYFGEISILNMGTAGNRRTASVRSVGYSDLFVLSKKDMWDVL----KEYPAA 1000
            ||  .|:.|...|..|||::||...    :|.||:|....:.:::|.:|....::    ::....
Mosquito   443 DN--KVIKSFGRGVVFGELAILYKA----KRFASIRVTTGARVWLLERKVFQKIMMKSGRKEREE 501

  Fly  1001 RVR-LESIAVKR---LEK-YKKAPLEKVKYFNVVAMGRCQSTPG 1039
            .|| |.:::|.:   :|| :|.:.|.|.:::...:....|..||
Mosquito   502 NVRFLSTVSVLKDLEIEKLHKISDLLKREFYATGSTIIQQGDPG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	2/7 (29%)
		CAP_ED	890..1004	CDD:237999	29/118 (25%)
		DUF4655	1084..>1154	CDD:317882
AgaP_AGAP009798	XP_318891.4	Crp	387..>533	CDD:223736	40/159 (25%)
		CAP_ED	397..494	CDD:237999	28/110 (25%)
		Crp	505..>615	CDD:223736	10/41 (24%)
		CAP_ED	511..616	CDD:237999	9/35 (26%)
		PTZ00263	647..948	CDD:140289
		STKc_cGK	657..915	CDD:270724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910