DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and prkg1

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	XP_002935474.2	Gene:	prkg1 / 100494278	XenbaseID:	XB-GENE-966465	Length:	685	Species:	Xenopus tropicalis

Alignment Length:	383	Identity:	85/383 - (22%)
Similarity:	144/383 - (37%)	Gaps:	120/383 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   730 CLYHI-------IHKNNGFGSRNWVYHDSESADVVKQYLQSYYWCTLALTTIGDLPKPRSKGEYV 787
            |:|.:       |.|....||..:|..|.: .:|.|:        ::.|.|:|       .|: |
Frog   132 CMYPVEYGKDSCIIKEGDVGSLVYVMEDGK-VEVTKE--------SVKLCTMG-------PGK-V 179

  Fly   788 FVILQLLFGLMLFATVLGHVANIVTSV---SAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWF 849
            |..|.:|:.....|||     ..:|:|   :..|:.||       |.|        ::..:||..
Frog   180 FGELAILYNCTRTATV-----KTLTNVKLWAIDRQCFQ-------TIM--------MRTGLIKHT 224

  Fly   850 DYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVL---- 910
            :|                              ::.||.|..||:...    |:|.:|..||
Frog   225 EY------------------------------MEFLKSVPTFQSLPE----EIVSKLADVLEETH 255

  Fly   911 FSPGDYICRKGEVGKEMYIVNRGRLQVVADNG----KTVMASLKAGSYFGEISILNMGTAGNRRT 971
            :..||||.|:|..|...:|:::|::.|..::.    ...:.:|..|.:|||.::    ...:.||
Frog   256 YESGDYIIRQGARGDTFFIISKGKVNVTREDSPGEDPIFLRTLGKGDWFGEKAL----QGEDVRT 316

  Fly   972 ASVRSVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRLEKYK-KAPLE---------KVKYF 1026
            |:|.:.......|:.:    |..|.....   |:.::.|..|..: ||..|         |:..|
Frog   317 ANVIAAEAVTCLVIDR----DSFKHLIGG---LDDVSNKAYEDAEAKAKYEAEAAFFGNLKLADF 374

  Fly  1027 NVVAMGRCQSTPGLVESCGRTSLEEMWLPPATAGASSLM---HHHQALQQQHQASQQQ 1081
            |::      .|.| |...||..|.::........|..::   |.....||:|..|::|
Frog   375 NII------DTLG-VGGFGRVELVQLKSDECKTFAMKILKKRHIVDTRQQEHIRSEKQ 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	23/98 (23%)
		CAP_ED	890..1004	CDD:237999	29/121 (24%)
		DUF4655	1084..>1154	CDD:317882
prkg1	XP_002935474.2	DD_cGKI-beta	4..55	CDD:213375
		CAP_ED	117..226	CDD:237999	30/130 (23%)
		CAP_ED	236..340	CDD:237999	29/115 (25%)
		STKc_cGK	380..640	CDD:270724	12/47 (26%)
		S_TK_X	635..>678	CDD:214529
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910