DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and cnga1

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	XP_017950934.1	Gene:	cnga1 / 100491997	XenbaseID:	XB-GENE-950954	Length:	708	Species:	Xenopus tropicalis

Alignment Length:	467	Identity:	223/467 - (47%)
Similarity:	312/467 - (66%)	Gaps:	10/467 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   545 GQPHHQKPRRTASQRIRAATAARKLHFVFDPAGRLCYYWSMVVSMAFLYNFWVIIYRFAFQEINR 609
            |:...:|.:....::    ...:|..||.||:|.|.|.|...::|..:||:.:||.|..|.|:.:
Frog   148 GKAEKEKEKEKEKEK----EIKKKDIFVIDPSGNLYYNWLFCITMPVMYNWTMIIARACFDELQQ 208

  Fly   610 RTIAIWFCLDYLSDFLYLIDILFHFRTGYLEDGVLQTDALKLRTHYMNSTIFYIDCLCLLPLDFL 674
            ..:.:||.|||:||.:|:.|:....||||||.|:|..|.:|||..|..:..|.:|.|.::|.|.|
Frog   209 DYLELWFFLDYMSDAIYIADMFVRTRTGYLEQGLLVRDEVKLRDKYKMTMQFKLDVLSIIPTDIL 273

  Fly   675 YLSIGFN-SILRSFRLVKIYRFWAFMDRTERHTNYPNLFRSTALIHYLLVIFHWNGCLYHIIHKN 738
            ||..|.| ..||..:|:::.|.:.|..|||..|||||:||.:.||.|:::|.|||.|:|:.|.|.
Frog   274 YLQFGLNYPELRLNKLLRVARMFEFFQRTETRTNYPNIFRISNLIMYIVIIIHWNACVYYSISKA 338

  Fly   739 NGFGSRNWVYHDS---ESADVVKQYLQSYYWCTLALTTIGDLPKPRSKGEYVFVILQLLFGLMLF 800
            .|||...|||.::   |...:.::|:.|.||.||.|||||:.|.|....|:.||:...|.|:::|
Frog   339 IGFGEDTWVYPNTSHPEYGRLARKYVYSLYWSTLTLTTIGETPPPVQDSEFWFVVADFLVGVLIF 403

  Fly   801 ATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQKCSDEERAV 865
            ||::|:|.:::::::|||.|||.::|.:|.||..|:|...|:.:|||||||||..:|..||...:
Frog   404 ATIVGNVGSMISNMNAARAEFQGRIDAIKQYMHFRKVSKDLEKRVIKWFDYLWTNKKAVDEREVL 468

  Fly   866 SCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYIV 930
            ..|||||:|||||||||||||:|.||.:.|||.|.||||:|:|.::||||||||||::|:||||:
Frog   469 KYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLIELVLKLQPQVYSPGDYICRKGDIGREMYII 533

  Fly   931 NRGRLQVVADNGKTVMASLKAGSYFGEISILNM--GTAGNRRTASVRSVGYSDLFVLSKKDMWDV 993
            ..|:|.||||:|.|....|..|||||||||||:  ..|||||||:::|:||||||.|||.|:.:.
Frog   534 KEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEA 598

  Fly   994 LKEYPAARVRLE 1005
            |.|||.|:..||
Frog   599 LTEYPDAKAMLE 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	100/241 (41%)
		CAP_ED	890..1004	CDD:237999	70/115 (61%)
		DUF4655	1084..>1154	CDD:317882
cnga1	XP_017950934.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5440
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45638
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020