Protein Alignment CG42260 and hcn1

DIOPT Version :9

• Sequence 1: NP_001356969.1
• Gene: CG42260 / 37614
• FlyBaseID: FBgn0259145
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: XP_031750156.1
• Gene: hcn1 / 100490760
• XenbaseID: XB-GENE-950265
• Length: 839
• Species: Xenopus tropicalis
• Alignment Length: 874
• Identity: 219/874 - (25%)
• Similarity: 365/874 - (41%)
• Gaps: 158/874 - (18%)

  Fly   467 RYPRSRSQQQGHHNAAQQAHHPYQLQHSASTVSHHPH-------AHGPPSQG--GPGGPGPPHGG 522
            ::..|.:..:...|...|......|..|.|:|..|.:       |...|..|  ...||..|||.
 Frog     4 KFNSSTNSSRDDGNNVLQGKAEKSLTASTSSVKEHGNSVCFKTDAADDPVVGFEDAEGPSRPHGF 68

  Fly   523 HPHHPHHGGAGSGGGSGPGSH-------GGQPHHQKPRRTASQRIRAATAARKLHFVFDPAGRLC 580
            ....       .|....||.:       |.|...:|.:    :|::.|..     ::..|.....
 Frog    69 MQRQ-------FGSLMQPGVNKFSLRMFGSQKAVEKEQ----ERVKTAGV-----WIIHPYSDFR 117

  Fly   581 YYWSMVVSMAFLYNFWVIIYRFAFQEINRRTIAIWFCLDYLSDFLYLIDILFHFRTG-YLEDG-- 642
            :||.:::.:..:.|..:|.....|  ...:|...|...:..||.::|.|:..:|||| .:||.
 Frog   118 FYWDLIMLIMMVGNLVIIPVGITF--FTEQTTTPWIIFNVASDTVFLFDLFMNFRTGIVIEDNSE 180

  Fly   643 -VLQTDALKLRTHYMNSTIFYIDCLCLLPLDFLYL------------------SIGFNSILRSFR 688
             :|....:|:  :|:.|. |.:|.:..:|:|:::|                  .:.|..||...|
 Frog   181 IILDPKVIKM--NYLKSW-FVVDFISSIPVDYIFLIVEKGMDSEVYKTARALRIVRFTKILSLLR 242

  Fly   689 LVKIYRFWAFMDRTER--HTNY---PNLFRSTALIHYLLVIFHWNGCLYHIIHKNNGFGSRNWV- 747
            |:::.|...::.:.|.  |..|   ..:.|...||..:|::.||:|||..::.....|....||
 Frog   243 LLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQEFPPDCWVS 307

  Fly   748 ----YHDSESADVVKQYLQSYYWCTLALTTIG-DLPKPRSKGEYVFVILQLLFGLMLFATVLGHV 807
                .:||..    |||..:.:.....:..|| ....|.|..:....:|.::.|...:|..:||.
 Frog   308 LNNMVNDSWG----KQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHA 368

  Fly   808 ANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQKCSDEERAVSCLPDKL 872
            ..::.|:.::|:::|.|...|:.||...::|:.::.|:..::::.: ..|..||:..::.|.|.|
 Frog   369 TALIQSLDSSRRQYQEKYKQVEQYMSFHKLPSDMRQKIHDYYEHRY-QGKIFDEDNILNELNDPL 432

  Fly   873 KAEIAINVHLDTL-KRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEVGKEMYIVNRGRLQ 936
            :.|| :|.:...| ..:.:|.|.:..|:..::.:|:..:|.|||||.|:|.|||:||.:..|...
 Frog   433 REEI-VNFNCRKLVATMPLFANADPNFVTAMLSKLKFEVFQPGDYIIREGAVGKKMYFIQHGVAG 496

  Fly   937 VVADNGKTVMASLKAGSYFGEISILNMGTAGNRRTASVRSVGYSDLFVLSKKDMWDVLKEYPAAR 1001
            |:..:.|.:  .|..|||||||.:|..|    |||||||:..|..|:.||.::..:||:|||..|
 Frog   497 VITKSSKEM--KLTDGSYFGEICLLTKG----RRTASVRAETYCRLYSLSVENFNEVLEEYPMMR 555

  Fly  1002 VRLESIAVKRLEKY-KKAPLEKVKY--------FN---------VVAMGR----------CQSTP 1038
            ...|::|:.||::. ||..:.:.::        ||         ::...|          .|..|
 Frog   556 RAFETVAIDRLDRIGKKNSILQQRFQKDLNTGIFNNQESEILKQMLTQDREMVEGHPSVSYQQLP 620

  Fly  1039 GLVESCGRTSLEEMWLPPATAGASSLMHHHQALQQQHQASQQQPHRQESTQTSSQTHGYSPRSYA 1103
            .| .|...:||......|....|:||.|          .:.|.|  ..|.||..|...:||.|:.
 Frog   621 AL-NSSTSSSLRMRTRSPPVYNANSLSH----------GNLQSP--TPSPQTPQQAVVFSPSSFT 672

  Fly  1104 DRLARATDSPRSVSPSAHGSEERPRSRTTSHHSIRPQSQPSHTGHICDSSSQL-ECYGAGVGGAG 1167
            .    |..||...||.| |...:..|.|.|..|:..|.|.:      ..:||: |.:.:....|.
 Frog   673 S----AACSPSVQSPLA-GRTFQYSSLTASQLSLIQQQQQA------SGASQIHEVHKSAQALAN 726

  Fly  1168 GGTT----PLLGSHEVLEDEIKRLRERLHTVESEN-----------QALNTKLSQQQWDLENRLA 1217
            ...|    ||..|...|..||..|..:.|....|:           ||..|: |..:.::..|:|
 Frog   727 TNLTREVRPLSASQPSLPHEISTLGSKPHPTVGESLASLPQPISNVQAAGTQ-SGSRSNIPPRVA 790

  Fly  1218 EIEMQICG------VSSTSSVDPENETEE 1240
            .......|      |.:|:...|...|::
 Frog   791 LFRQMSSGALPPARVGATTQPSPAPPTKD 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	62/270 (23%)
		CAP_ED	890..1004	CDD:237999	47/113 (42%)
		DUF4655	1084..>1154	CDD:317882	20/69 (29%)
hcn1	XP_031750156.1	Ion_trans_N	73..115	CDD:400630	9/50 (18%)
		PLN03192	108..>587	CDD:215625	134/495 (27%)
		CAP_ED	450..558	CDD:237999	47/113 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910