DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42260 and LOC100334297

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	XP_017208463.1	Gene:	LOC100334297 / 100334297	-ID:	-	Length:	908	Species:	Danio rerio

Alignment Length:	677	Identity:	182/677 - (26%)
Similarity:	297/677 - (43%)	Gaps:	115/677 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   550 QKPRRTASQRIRAATAARKLHFVFDPAGRLCYYWSMVVSMAFLYNFWVIIYRFAFQEINRRTIAI 614
            ||......:|::.|.     :::..|.....:||.:::.:..:.|..:|.....|  .:.:|...
Zfish    94 QKAVEKEQERVQTAG-----YWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITF--FSEQTTTS 151

  Fly   615 WFCLDYLSDFLYLIDILFHFRTGYL--EDGVLQTDALKLRTHYMNSTIFYIDCLCLLPLDFLYLS 677
            |...:..||.::|:|::.:||||.:  |...:..|...::.:|:.|. |.:|.|..:|:|:::|.
Zfish   152 WLVFNVASDTIFLVDLVMNFRTGIVNEESSEIILDPKVIKMNYLKSW-FVVDFLSSIPVDYIFLI 215

  Fly   678 I--GFNS----------------ILRSFRLVKIYRFWAFMDRTER--HTNY---PNLFRSTALIH 719
            :  ||:|                ||...||:::.|...::.:.|.  |..|   ..:.|...||.
Zfish   216 VEKGFDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIG 280

  Fly   720 YLLVIFHWNGCLYHIIHKNNGFGSRNWV-----YHDSESADVVKQYLQSYYWCTLALTTIG-DLP 778
            .:|::.||:|||..::.....|....||     .:||..    |||..:.:.....:..|| ...
Zfish   281 MMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWG----KQYSYALFKAMSHMLCIGYGAR 341

  Fly   779 KPRSKGEYVFVILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQV 843
            .|.|..:....:|.::.|...:|..:||...::.|:.::|:::|.|...|:.||...::|..::.
Zfish   342 APVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQ 406

  Fly   844 KVIKWFDYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTL-KRVEIFQNTEAGFLCELVLRLR 907
            |:..::::.: ..|..||:..::.|.|.||.|| :|.:...| ..:.:|.|.:..|:..::.:|:
Zfish   407 KIHDYYEHRY-QGKIFDEDSILNELNDPLKEEI-VNFNCRKLVATMPLFANADPNFVTGMLSKLK 469

  Fly   908 PVLFSPGDYICRKGEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNMGTAGNRRTA 972
            ..:|.|.|||.|:|.|||:||.:..|...|:....|.:  .|..|||||||.:|..|    ||||
Zfish   470 FEVFQPNDYIIREGTVGKKMYFIQHGVASVITKFNKEL--KLTDGSYFGEICLLTKG----RRTA 528

  Fly   973 SVRSVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRLEKY-KKAPLEKVKY--------FN- 1027
            |||:..|..||.||.....:||:|||..|...|::|:.||::. ||..|...|:        ||
Zfish   529 SVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQKFQKDLNAGVFNT 593

  Fly  1028 ----------------VVAMGRCQSTPGL--VESCGRTSLEEMWLPP-ATAGASSLMHHHQALQQ 1073
                            |:.:.|.||..|:  ....|.:.:.....|| |||         .|:..
Zfish   594 QENELLKQIIRQDREMVMMVDRKQSVTGMNSTPMSGNSIINSPAQPPFATA---------TAILG 649

  Fly  1074 QHQASQQQPHRQESTQTSSQTHGYSPRSYADRLARATDSPRSVSPSAHG--SEERPRSRTTSHHS 1136
            .:|..||......||..:....|..|.|..     .|.|..|||   ||  |...|...|
Zfish   650 NNQLQQQAAPLSYSTSATITPSGRVPPSQG-----VTFSAPSVS---HGNLSSSSPNPPT----- 701

  Fly  1137 IRPQSQP--------SHTGHICDSSSQ 1155
              |..||        |.|..||....|
Zfish   702 --PLQQPAGAIMSPCSFTTSICSPPVQ 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	63/268 (24%)
		CAP_ED	890..1004	CDD:237999	47/113 (42%)
		DUF4655	1084..>1154	CDD:317882	22/79 (28%)
LOC100334297	XP_017208463.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910