Protein Alignment CG42260 and kcnh5b

DIOPT Version :9

• Sequence 1: NP_001356969.1
• Gene: CG42260 / 37614
• FlyBaseID: FBgn0259145
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: XP_002664253.1
• Gene: kcnh5b / 100331767
• ZFINID: ZDB-GENE-090319-1
• Length: 1005
• Species: Danio rerio
• Alignment Length: 573
• Identity: 134/573 - (23%)
• Similarity: 248/573 - (43%)
• Gaps: 80/573 - (13%)

  Fly   569 LHFVFDPAGRLCYY---WSMVVSMAFLYNFWVIIYRFAFQEINRRTIAIWFCLDYLSDFLYLIDI 630
            ||:        |.:   |..|:.:...|...::.|..:|:  .::....|..||.:.|.::|:||
Zfish   209 LHY--------CTFKTTWDWVILILTFYTAIMVPYNVSFK--TKQNNVTWLVLDSVVDVIFLVDI 263

  Fly   631 LFHFRTGYL-EDGVLQTDALKLRTHYMNSTIFYIDCLCLLPLD----FLYLSIGFNSILRSFRLV 690
            :.:|.|.:: ..|.:.:|...:|.:|: .|.|.||.|..||.|    |..:..|.:|:..|.::|
Zfish   264 VLNFHTTFVGPGGEVISDPNLIRMNYL-KTWFVIDLLSCLPYDIINAFENVDEGISSLFSSLKVV 327

  Fly   691 KIYRFWAFMDRTERHTNYPNLFRSTALIHYLLVIF----HWNGCLYHII-------HKNNGFGSR 744
            ::.|......:.:.:..|     ..|::..|:.:|    ||..|:::.|       .:.|...:.
Zfish   328 RLLRLGRVARKLDHYLEY-----GAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEQTNTIKTD 387

  Fly   745 NWVYHDSES--------ADVVKQ----------YLQSYYWCTLALTTIG-DLPKPRSKGEYVFVI 790
            :|::..:.|        |....|          |:.|.|:...:||||| ....|.:.||.:|.:
Zfish   388 SWLFQLATSIGSPYRYNASGTGQWEGGPGKDSLYITSLYFTMTSLTTIGFGNIAPTTDGEKIFSV 452

  Fly   791 LQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLT 855
            ..::.|.:|:||:.|:|..|...:.|....:...|:.|:.::::.:||..|..:|:.:....|..
Zfish   453 AMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSM 517

  Fly   856 QKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRK 920
            .|..|.|:.:|..|..::|:|.::::.........|:....|.|..|.:..:.:..:|||.|...
Zfish   518 SKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRSLAVEFQMIHSAPGDLIFHA 582

  Fly   921 GEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNMGTAGNRRTASVRSVGYSDLFVL 985
            ||....:..|..|.|:|:.|:  .|:|.|..|..||::.......|  ...|:||::.|.||.::
Zfish   583 GESVDLLCFVVSGSLEVIQDD--EVIAILGKGDVFGDVFWKETTLA--HSCANVRALTYCDLHII 643

  Fly   986 SKKDMWDVLKEYPA------------ARVRLESIAVKRLEKYKKAPLEKVKYFNVVAMGRCQSTP 1038
            .::.:..||..|.|            ..:| :....:::...||...|:.:..|.|.:......|
Zfish   644 KREALLKVLDFYTAFANSFSRNLFLTCNLR-KRFVFRKIIDVKKEEEERQRSKNEVPLTIPVDHP 707

  Fly  1039 GLVESCGRTSLEEMWLPPATAGASSLMHHHQALQQQHQASQQQPHRQESTQTS 1091
              |....:...::..|  ...|||:     |...:::|...|||.|.....||
Zfish   708 --VRKLFQKFKQQKEL--RNQGASA-----QLDLEKNQHHLQQPARMSKPHTS 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	65/275 (24%)
		CAP_ED	890..1004	CDD:237999	32/125 (26%)
		DUF4655	1084..>1154	CDD:317882	3/8 (38%)
kcnh5b	XP_002664253.1	PAS	37..131	CDD:238075
		PAS_3	40..127	CDD:285623
		Ion_trans	233..481	CDD:278921	62/255 (24%)
		Ion_trans_2	<421..475	CDD:285168	19/53 (36%)
		Crp	546..>666	CDD:223736	32/123 (26%)
		CAP_ED	552..662	CDD:237999	32/113 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910