DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13526 and CALML5

DIOPT Version :9

Sequence 1:	NP_611714.1	Gene:	CG13526 / 37613	FlyBaseID:	FBgn0034774	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	NP_059118.2	Gene:	CALML5 / 51806	HGNCID:	18180	Length:	146	Species:	Homo sapiens

Alignment Length:	139	Identity:	42/139 - (30%)
Similarity:	74/139 - (53%)	Gaps:	3/139 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ELTNEHIDELRDAFEKYDLDSNGTLSANEVRLALISVGYEITEAELYDLIHSVAVRDEERLDLKK 72
            |||.|...:.:.||...|.|.|||::|.|:..||.:.|..::||:|..||..|....:..:..::
Human     4 ELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQE 68

  Fly    73 FIRMMAPRMANVDSDKSLCRTFNMIDRDRDGYVTVQDVRAIMVVLGEVVTDDDIKDICQAVDMDG 137
            |:.......|.::   .|...|...|:|.||::||.::|..|..||:.:..:::..:.:..|:|.
Human    69 FLTAAKKARAGLE---DLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQ 130

  Fly   138 DGRISLRDF 146
            |||::..:|
Human   131 DGRVNYEEF 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13526	NP_611714.1	PTZ00184	7..152	CDD:185504	42/139 (30%)
		EFh	16..78	CDD:238008	19/61 (31%)
		EFh	92..151	CDD:238008	17/55 (31%)
CALML5	NP_059118.2	PTZ00184	1..143	CDD:185504	42/139 (30%)
		EFh	12..74	CDD:238008	19/61 (31%)
		EFh	82..144	CDD:238008	18/58 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23050
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.970