DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13526 and MYL5

DIOPT Version :9

Sequence 1:	NP_611714.1	Gene:	CG13526 / 37613	FlyBaseID:	FBgn0034774	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	XP_006713949.1	Gene:	MYL5 / 4636	HGNCID:	7586	Length:	328	Species:	Homo sapiens

Alignment Length:	152	Identity:	30/152 - (19%)
Similarity:	69/152 - (45%)	Gaps:	27/152 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FSGNELTNEHIDELRDAFEKYDLDSNGTLSANEVRLALISVGYEITEAELYDLIHSVAVRDEERL 68
            ||..|.|  .|.|.::||...|.:.:|.:...:::....|:|             ...|:|:| |
Human   179 FSNFEQT--QIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLG-------------KTNVKDDE-L 227

  Fly    69 D--LKK---------FIRMMAPRMANVDSDKSLCRTFNMIDRDRDGYVTVQDVRAIMVVLGEVVT 122
            |  ||:         |:.:...:::..|:::::...|.|:|.|..|.:..:.::.:::...:.:|
Human   228 DAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMT 292

  Fly   123 DDDIKDICQAVDMDGDGRISLR 144
            .:::..:.|...:|..|.:..:
Human   293 AEEVDQMFQFASIDVAGNLDYK 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13526	NP_611714.1	PTZ00184	7..152	CDD:185504	28/149 (19%)
		EFh	16..78	CDD:238008	15/72 (21%)
		EFh	92..151	CDD:238008	9/53 (17%)
MYL5	XP_006713949.1	FRQ1	170..314	CDD:227455	30/150 (20%)
		EFh	189..247	CDD:238008	15/71 (21%)
		EFh	263..314	CDD:238008	9/50 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010