Protein Alignment CG30259 and drc2

DIOPT Version :10

• Sequence 1: NP_611708.2
• Gene: CG30259 / 37606
• FlyBaseID: FBgn0050259
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001002603.1
• Gene: drc2 / 368824
• ZFINID: ZDB-GENE-030616-358
• Length: 492
• Species: Danio rerio
• Alignment Length: 511
• Identity: 138/511 - (27%)
• Similarity: 246/511 - (48%)
• Gaps: 54/511 - (10%)

  Fly     3 KKGKGKGNKLANMSEEERARYLQMRADMEEETRRRKMQLISMYMKNKLKREDAFGRLNMAKINQE 67
            |.||..|.|||.::||||..|:|.:|..|||..:||..:::.::|:||::|:....||:.|:.|:
Zfish     4 KAGKKGGGKLAGLTEEERLLYMQQKAQAEEEIAKRKEDMLTHFLKDKLQKEEKNTVLNLHKLRQQ 68

  Fly    68 WRSILRQVKIQELRREIVDVESFFQEALKRKDQVIHRLIAHIESTEDMYANLQQSHMENITRIVD 132
            ||::|.|.||.|||.::..:...|:..|..||.:|..|...:...|.....::.||:.|:..:::
Zfish    69 WRAVLTQTKIAELRNDMSVLSQTFERVLDYKDNIIRSLQVDLSERELQSELMRSSHLHNVDCLLE 133

  Fly   133 THRDRIEFFRTIYEDDKQAVLSQWEQDSAAFKEMHAQKQQQLECVFYQLEE---NTDGGIRDNHE 194
            .|:.|:......::...:.:.|::..:.......|.|:...|:.|.:.:|:   :.||..:.:::
Zfish   134 IHKSRLAQLEFNFKSSLEELSSEYNTEREQILSQHQQECVDLDNVMFSMEKHYSDLDGEAKRDYQ 198

  Fly   195 ----RFLDRCEDLKSGMQLQLEQITSRGEARLEKLWQEYQGVLAGYCQHIEGFYSEYVDLKQRDE 255
                :...|..|.|..::.|::.:       :|||||:.|.||..|.:..........||..:|.
Zfish   199 STRNQIKKRNFDDKQAVKEQMDGV-------VEKLWQDQQQVLNHYNESTRDKIITTDDLMNKDV 256

  Fly   256 EAALQISQQTHEIEHLVDQLTNLRLVSEEFYIKQQGQLEQRQAIKQQLTERLRELRTCVEQEVAR 320
            ::|.:|......|:.|.|.::..|           |||...|..|  ..|:||..|    .|:|:
Zfish   257 QSAKEIDSLKKHIQKLQDSISTFR-----------GQLSSGQTDK--TAEQLRSER----DELAQ 304

  Fly   321 DHQLFKL---------------MSVESYHALEFLQETVAKGETLAQLSAVCAKMETQRERM--FQ 368
            :.|.|::               ::|:|..|.:.|||.||:||.|.:...:|.|:||:.|::  |.
Zfish   305 EVQHFRVQLNAAQAIRKKHITKLTVQSNDATKKLQEIVARGERLLRQCEMCCKLETEHEKVLPFY 369

  Fly   369 LPEISKEIIEIRDIEDQGNGSLTDPATDLLKDEVAVVPQMESFWRRVNNVAVDVACLKQQKRRLE 433
            ...:|||  |.:..:.:...|..:..|.|:.|    ...:..||:|.|.|.:|..|:|::|..|.
Zfish   370 KSSLSKE--EQKQEKAKAMESSNEKLTQLMHD----YSPLAKFWQRYNKVELDCLCVKREKLLLL 428

  Fly   434 AENSQLKTQLQDYLVNLNIANGSNSHVHSYLARRPKSMSVDRVSRLQLQPKLVKSA 489
            .||.:|:..|:.||..:::::.|.......:...|.........|.|.:..:|:.|
Zfish   429 QENERLRLFLKQYLDEVSVSDESFQQQKLLVVSSPALQDTAATDRHQQKRHVVQEA 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30259	NP_611708.2	NYD-SP28	26..127	CDD:464307	32/100 (32%)
		SMC_prok_B	47..>376	CDD:274008	91/352 (26%)
drc2	NP_001002603.1	NYD-SP28	27..128	CDD:464307	32/100 (32%)
		flgK	<230..>302	CDD:236270	22/88 (25%)
		NYD-SP28_assoc	<403..442	CDD:464309	14/38 (37%)