Protein Alignment CG30259 and Ccdc65

DIOPT Version :10

• Sequence 1: NP_611708.2
• Gene: CG30259 / 37606
• FlyBaseID: FBgn0050259
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_705738.1
• Gene: Ccdc65 / 105833
• MGIID: 2146001
• Length: 493
• Species: Mus musculus
• Alignment Length: 510
• Identity: 146/510 - (28%)
• Similarity: 263/510 - (51%)
• Gaps: 51/510 - (10%)

  Fly     1 MGKKGKGKGNKLANMSEEERARYLQMRADMEEETRRRKMQLISMYMKNKLKREDAFGRLNMAKIN 65
            |.||||......|.:|||::....|.:...:||..::|.:|::.::|:||.:|:....||:.|||
Mouse     1 MSKKGKKPKLPKAPLSEEDQLLIFQQKMLADEEAAKKKERLLTQFLKDKLAKEEHNSALNLNKIN 65

  Fly    66 QEWRSILRQVKIQELRREIVDVESFFQEALKRKDQVIHRLIAHIESTEDMYANLQQSHMENITRI 130
            .:||:|||:||.:||.::|..:...|:..:..||.||..|...:...|:.||:..:||:.||.::
Mouse    66 TQWRTILREVKTRELHQDIEILSQTFERVVDCKDSVIKSLAKDLTEAEEQYAHALRSHLHNIDQL 130

  Fly   131 VDTHRDRIEFFRTIYEDDKQAVLSQWEQDSAAFKEMHAQKQQQLECVFYQLEENTDGGIRDNHER 195
            :...|.|:......|..:.:.:..::|.:.....:.|.::...|:.||..:|:|......::...
Mouse   131 LTLQRRRLGLLEENYNMELEVLTKEFETERKLIIDHHEKEMHYLQDVFMAMEQNYIDSEYESKLE 195

  Fly   196 FLDRCEDLKSG-------MQLQLEQITSRGEARLEKLWQEYQGVLAGYCQHIEGFYSEYVDLKQR 253
            |....:|||:.       ::||||.|       :|.||:.:|..|..|....|.....:..||.:
Mouse   196 FQSMWDDLKNKNLEEKHFLRLQLENI-------VEDLWRRFQDALKNYTDATEDRKIAFEYLKVK 253

  Fly   254 DEEAALQISQQTHEIEHLVDQLTNL--RLVSEEFYIKQQGQLEQRQAI---KQQLTERLRELRTC 313
            ||:::.:|..|..:|:.|.:.:..|  ::|:.    .::|:. |.|.|   |:.:..:||:|:
Mouse   254 DEKSSKEIETQMKKIQKLQETIGILKGKIVAH----SREGEW-QNQCIRNNKELVHVQLRKLK-- 311

  Fly   314 VEQEVAR---DHQLFKLMSVESYHALEFLQETVAKGETLAQLSAVCAKMETQRERMFQLPEISKE 375
            |::..||   ...|.|| ::||...|:.|::.|.|||.:.:|:.:|.|.||:.|::  ||..|..
Mouse   312 VQRTQARTLSQENLVKL-TLESNATLKALKKVVEKGEKILKLAEICRKFETEEEKV--LPFYSSV 373

  Fly   376 IIEIRDIEDQGNGSLTDPATDLLKDEVAVVPQ---MESFWRRVNNVAVDVACLKQQKRRLEAENS 437
            :..    |:|....|.:| .|:.:|...::..   ||:||:|.|.|.::|..|:.::.:|...:|
Mouse   374 LTP----EEQEEAKLQNP-EDITEDLAKIMMDYAGMENFWKRYNKVKLEVLSLQHRRLQLLDISS 433

  Fly   438 QLKTQLQDYLVNLNIANGSNSHVHSYLARRPKSMSVDRVSRL-QLQPKLVKSAQP 491
            :|:..|:.||..:::::...||::....       |:..|.| ||.|   .||||
Mouse   434 KLREMLKQYLDGISVSDEVLSHLNPLFV-------VNHRSNLPQLPP---PSAQP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30259	NP_611708.2	NYD-SP28	26..127	CDD:464307	34/100 (34%)
		SMC_prok_B	47..>376	CDD:274008	99/343 (29%)
Ccdc65	NP_705738.1	NYD-SP28	26..127	CDD:464307	34/100 (34%)