DRSC/TRiP Functional Genomics Resources

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Protein Alignment robo1 and nectin1b

DIOPT Version :9

Sequence 1:NP_476899.1 Gene:robo1 / 37603 FlyBaseID:FBgn0005631 Length:1395 Species:Drosophila melanogaster
Sequence 2:NP_001161041.1 Gene:nectin1b / 557665 ZFINID:ZDB-GENE-090224-2 Length:541 Species:Danio rerio


Alignment Length:327 Identity:66/327 - (20%)
Similarity:112/327 - (34%) Gaps:94/327 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   269 GQTATFHC-SVGGDPPPK---VLWKK----EEGNIPVS--------------RARILH------- 304
            |.|....| .:.|.||.|   |.|:|    .:.|:.::              |....|       
Zfish    77 GDTVELKCLFINGKPPVKISQVTWQKLINGTKQNVAIANPALGVSVLTPFKDRVSFKHPAVRQRT 141

  Fly   305 ----DEKSLEISNITPTDEGTYVCE-----AHNNVGQIS----AR--ASLIVHAPPNFTKRPSNK 354
                ::.::..|::..:||..|:||     |.|....::    ||  ..:.:.:|....:.|..|
Zfish   142 PSSLEDTTIVFSSLRLSDEAAYICEYTTFPAGNRENMVNLTVF
ARPVTKMTLTSPTIVARTPKRK 206

  Fly   355 KVGLNGVVQLP---CMASGNPPPSVF-W--TKEGVSTLMFPNSSHGRQHVAADGTLQITDVRQED 413
                     :|   ||::...||||. |  |.:|.:|.....:.:|.  |.......:...|:..
Zfish   207 ---------MPVATCMSANGKPPSVIKWDTTLKGEATFQETRNPNGT--VTVRSNYIVLPSRETH 260

  Fly   414 EGYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRI-K 477
            .....|......:..|..|.|.|   ...|...|:....|..|.:.:| .|.|.|..||...: :
Zfish   261 RQKLTCIVTYRSERFTDSVILNV
---QYEPEVKIEGFDGNWYLNRPNV-QLTCNADANPPVTVYQ 321

  Fly   478 WFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDS-------------GTYTCTASGERGETSWAATL 529
            |             .::.||  ..:::::.::             |||.|.|:...|..|....:
Zfish   322 W-------------KLLNGS--LPNNIEIKNNTLFFKGPVTYELGGTYVCEATNSIGTRSGLVEV 371

  Fly   530 TV 531
            .|
Zfish   372 NV 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
robo1NP_476899.1 Ig 56..151 CDD:299845
I-set 56..150 CDD:254352
I-set 157..251 CDD:254352
Ig2_Robo 159..251 CDD:143201
I-set 255..341 CDD:254352 23/115 (20%)
Ig3_Robo 272..341 CDD:143202 21/112 (19%)
IG_like 351..436 CDD:214653 20/90 (22%)
Ig 362..444 CDD:299845 19/87 (22%)
I-set 445..531 CDD:254352 19/99 (19%)
IGc2 459..521 CDD:197706 14/75 (19%)
FN3 549..637 CDD:238020
FN3 673..762 CDD:238020
fn3 770..855 CDD:278470
nectin1bNP_001161041.1 IG_like 70..183 CDD:214653 21/105 (20%)
Ig 80..184 CDD:299845 19/103 (18%)
Ig 187..283 CDD:299845 21/106 (20%)
IG_like 304..373 CDD:214653 16/84 (19%)
IGc2 304..363 CDD:197706 14/74 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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