DRSC/TRiP Functional Genomics Resources

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Protein Alignment robo1 and Pvr

DIOPT Version :9

Sequence 1:NP_476899.1 Gene:robo1 / 37603 FlyBaseID:FBgn0005631 Length:1395 Species:Drosophila melanogaster
Sequence 2:NP_081790.1 Gene:Pvr / 52118 MGIID:107741 Length:408 Species:Mus musculus


Alignment Length:329 Identity:76/329 - (23%)
Similarity:126/329 - (38%) Gaps:65/329 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 PKDQVMLYGQTATFHCSVGGDPP---PKVLWKKEEGNIPVSRARILHDEK--------------- 307
            |.:...:.|.:.|.|||:..:..   .::.|.|::.....:...:.|.:|               
Mouse    35 PYNSTGVLGGSTTLHCSLTSNENVTITQITWMKKDSGGSHALVAVFHPKKGPNIKEPERVKFLAA 99

  Fly   308 -------SLEISNITPTDEGTYVCE-AHNNVGQISARASLIVHAPPNFTK---RPSNKKVGLNGV 361
                   ||.|||::..|||.|.|: |....|..|..|.|.|.|.|..|.   .||...: |..|
Mouse   100 QQDLRNASLAISNLSVEDEGIYECQIATFPRGSRSTNAWLKVQARPKNTAEALEPSPTLI-LQDV 163

  Fly   362 VQLPCM-ASGNPPPSVFWTKEGVSTLMFPNSSHG--RQHVAADGTLQITDV------RQEDEGYY 417
            .:  |: |:|:||..:.|...       .|.||.  ::..:..||..:|..      ||.|....
Mouse   164 AK--CISANGHPPGRISWPSN-------VNGSHREMKEPGSQPGTTTVTSYLSMVPSRQADGKNI 219

  Fly   418 VCSAFSVVDSSTVRVF--LQVSSLDERPPPIIQIGPANQTLPKG-SVATLPCRATGNPSPRIKWF 479
            .|:    |:..:::..  |.|:.....||..:.|...:.....| :..||.|.|...|:|.:..:
Mouse   220 TCT----VEHESLQELDQLLVTLSQPYPPENVSISGYDGNWYVGLTNLTLTCEAHSKPAPDMAGY 280

  Fly   480 HDGHAVQAGNRYSII--QGSSLRVDDLQLSDSGT-YTCTASGERGETSWAATLTV-EKP----GS 536
            :  .:...|:..:.:  ||:.|.:..::...:.| ..|..:...|.......:.| |||    .:
Mouse   281 N--WSTNTGDFPNSVKRQGNMLLISTVEDGLNNTVIVCEVTNALGSGQGQVHIIVKEKPENMQQN 343

  Fly   537 TSLH 540
            |.||
Mouse   344 TRLH 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
robo1NP_476899.1 Ig 56..151 CDD:299845
I-set 56..150 CDD:254352
I-set 157..251 CDD:254352
Ig2_Robo 159..251 CDD:143201
I-set 255..341 CDD:254352 25/105 (24%)
Ig3_Robo 272..341 CDD:143202 23/94 (24%)
IG_like 351..436 CDD:214653 22/95 (23%)
Ig 362..444 CDD:299845 19/92 (21%)
I-set 445..531 CDD:254352 15/89 (17%)
IGc2 459..521 CDD:197706 13/65 (20%)
FN3 549..637 CDD:238020
FN3 673..762 CDD:238020
fn3 770..855 CDD:278470
PvrNP_081790.1 IG_like 35..141 CDD:214653 25/105 (24%)
Ig1_PVR_like 44..142 CDD:143195 23/97 (24%)
Ig2_Nectin-2_like 145..240 CDD:143327 25/108 (23%)
IG_like 262..333 CDD:214653 13/72 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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