DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment robo1 and Pvr

DIOPT Version :9

Sequence 1:NP_476899.1 Gene:robo1 / 37603 FlyBaseID:FBgn0005631 Length:1395 Species:Drosophila melanogaster
Sequence 2:NP_058772.2 Gene:Pvr / 25066 RGDID:3813 Length:412 Species:Rattus norvegicus


Alignment Length:318 Identity:73/318 - (22%)
Similarity:121/318 - (38%) Gaps:49/318 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 GETALLECG------------------PPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDG 215
            |.:.:|.|.                  |....|...:...|.|..:.|.:.:.|..:.....:..
  Rat    48 GGSTVLHCSLASKDNVTITQLTWMKRDPDGSHPSVAVFHPKKGPSISDPERVKFLVAKVYEDLRN 112

  Fly   216 GNLLISNVEPIDEGNYKC-IAQNLVGTRESS-YAKLIVQVK-PYFMKEPKDQVMLYGQTATFHCS 277
            .:|.|||:...|||.|:| ||....|::.:: :.|:..:.| .....||...:|  .|......|
  Rat   113 ASLAISNLRVEDEGIYECQIATFPTGSKSANVWLKV
FARPKNTAEALEPSPTLM--PQDVAKCIS 175

  Fly   278 VGGDPPPKVLWK----------KEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQ 332
            ..|.||.::.|.          ||.|:.|.:...|.:    |.:...:..|.....|...:...|
  Rat   176 ADGHPPGRITWSSNVNGSYREMKETGSQPGTTTVISY----LSMVPSSQADGTNITCTVEHESFQ 236

  Fly   333 ISARASLIVHAP----PNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVF-WTKEGVSTLMFPNSS 392
            ...:..||:..|    .:.:....|..:||.. |.|.|.|...|||:.: |:   .:|...|||:
  Rat   237 EPDQQPLILS
LPYPPEVSISGYEGNWYIGLTN-VNLTCEARSKPPPTNYSWS---TATGPLPNST 297

  Fly   393 HGRQHVAADGTLQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIG 450
            |.:::   ...|.|:.|...:...:||.|.:.:.|...:|.:.|....|..||...:|
  Rat   298 HFQEN---GSHLLISTVDDLNNTIFVCKAINALGSGQGQVTILVKEAS
EILPPKTSLG 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
robo1NP_476899.1 Ig 56..151 CDD:299845
I-set 56..150 CDD:254352
I-set 157..251 CDD:254352 22/101 (22%)
Ig2_Robo 159..251 CDD:143201 22/101 (22%)
I-set 255..341 CDD:254352 19/95 (20%)
Ig3_Robo 272..341 CDD:143202 15/78 (19%)
IG_like 351..436 CDD:214653 24/85 (28%)
Ig 362..444 CDD:299845 23/82 (28%)
I-set 445..531 CDD:254352 2/6 (33%)
IGc2 459..521 CDD:197706
FN3 549..637 CDD:238020
FN3 673..762 CDD:238020
fn3 770..855 CDD:278470
PvrNP_058772.2 IG_like 41..148 CDD:214653 21/99 (21%)
Ig1_PVR_like 49..148 CDD:143195 20/98 (20%)
Ig 152..246 CDD:299845 21/99 (21%)
IG_like 268..338 CDD:214653 21/76 (28%)
Ig <269..342 CDD:299845 22/78 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.