DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and SKIP1

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_568870.1	Gene:	SKIP1 / 835901	AraportID:	AT5G57900	Length:	300	Species:	Arabidopsis thaliana

Alignment Length:	187	Identity:	58/187 - (31%)
Similarity:	85/187 - (45%)	Gaps:	35/187 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 GLTSLKSINLSFCVSVTDSGLKHLA-RMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFC 433
            |||   .|.:..|   :|..|.:.| |.|.|:.|.:||..|::|..|..:......:..||:|:|
plant    90 GLT---KIRVRHC---SDHALSYAADRCPNLQVLAIRSSPNVTDASMTKIAFRCRSLKELDISYC 148

  Fly   434 DKISDQALTHIAQGLYRLRSLS------------------LNQC-QITDHGMLKIAKALHELENL 479
            .:||...|..|.:....||.|.                  |:.| |..|.....|.|.:..||:|
plant   149 HEISHDTLVMIGRNCPNLRILKRNLMDWSSRHIGSVPTEYLDACPQDGDTEADAIGKHMINLEHL 213

  Fly   480 NIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKLQKLNLGLWL 536
            .| |.||::.|||.::.|....|:.:||:||..|||:  ||...:.:|:      ||
plant   214 EI-QFSRLSVKGLASICEGCPKLEYLDLFGCVHLSSR--DITSNVSRLK------WL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689
		AMN1	<226..>334	CDD:187754
		leucine-rich repeat	236..256	CDD:275381
		leucine-rich repeat	263..288	CDD:275381
		leucine-rich repeat	289..314	CDD:275381
		leucine-rich repeat	315..347	CDD:275381
		AMN1	347..524	CDD:187754	55/173 (32%)
		leucine-rich repeat	348..373	CDD:275381	2/2 (100%)
		leucine-rich repeat	374..398	CDD:275381	6/24 (25%)
		leucine-rich repeat	399..424	CDD:275381	7/24 (29%)
		leucine-rich repeat	425..450	CDD:275381	8/24 (33%)
		leucine-rich repeat	451..475	CDD:275381	9/42 (21%)
		leucine-rich repeat	476..501	CDD:275381	11/24 (46%)
SKIP1	NP_568870.1	AMN1	<89..>253	CDD:187754	55/171 (32%)
		leucine-rich repeat	91..113	CDD:275381	8/27 (30%)
		leucine-rich repeat	114..139	CDD:275381	7/24 (29%)
		leucine-rich repeat	140..165	CDD:275381	8/24 (33%)
		leucine-rich repeat	187..209	CDD:275381	6/21 (29%)
		leucine-rich repeat	210..234	CDD:275381	11/24 (46%)
		leucine-rich repeat	235..260	CDD:275381	11/32 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810