DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and AT5G40470

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_198863.1	Gene:	AT5G40470 / 834045	AraportID:	AT5G40470	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	109/497 - (21%)
Similarity:	173/497 - (34%)	Gaps:	153/497 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 LFPELLEQIFEHLPVRDLGRAAQVCT--AWRDAAYAKSVWKGVEAKLHLKRSS------------ 202
            ||.|:|.:||..||......::...:  ::.........|      |.|.|:|
plant     5 LFDEILCEIFTRLPSSSSSSSSSSSSLPSFESVPLVSKRW------LRLYRASKTSMSLQFSPHD 63

  Fly   203 -------PSLFN---CL----VKRG--IKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADM- 250
                   ||:.|   ||    :.||  |......|....||...:....|.|:..|.|||:.::
plant    64 TSVITLLPSILNNHPCLSSLSIYRGVTIGTTPSRSDEEHLKAETIFSDELISIISSCCFNLRNLC 128

  Fly   251 -------------------------------NLGHAFSVDLPNLKTLDLSLCK------------ 272
                                           |.|..:.....:||.|.:.:|.
plant   129 FLINPVSSSSLVPLSTSLSLTSLSIELWKPQNSGFTWIALFSSLKELSIHVCSTSSPAFDFYPKS 193

  Fly   273 -------------------QITDTSLGRIAQHLRNLETLELGGCCNI-TNTGLLLIAWGLKKLKH 317
                               |..|..:..:.:..|.|:.|.|..|.:| ...||.     ||.|:.
plant   194 KPNPEVVELGLESVSLFGIQPDDNDVTWLWKSCRKLKKLSLRSCGSIGEEIGLC-----LKNLEE 253

  Fly   318 LNLRSCWHISD----------QGIGHLAGFSRETAEGNLQ----------LEYLGLQDCQRLSDE 362
            :.||:|..|.|          :.:..|......:.:|.:|          ||.|.|:....|:|:
plant   254 IELRTCRSIVDVVLLKVSEICESLKSLLIHDGGSKDGLVQFMSNARCYDTLERLDLRLPMDLTDD 318

  Fly   363 ALGHIAQGLTSLKSINLSFCVSVTDSGLKHLAR--MPKLEQLNLRSCDNISDIGMAYLTEGGSGI 425
            .|..:|.....|.::.|:.|:.||...||.||.  ...||:|:|.||:.|         |...|:
plant   319 HLVSLAANFKCLSTLRLTSCIFVTGFSLKALALSFSSSLEELSLLSCNAI---------ERERGL 374

  Fly   426 NSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQ-ITDHGMLKIAKALHELENLNIGQCSRITD 489
                           |..|.|.|.|||.|.|.:.: :.|..::.:..:.:.|..:.:..|..:|.
plant   375 ---------------LATIGQHLGRLRKLDLTRNEWLFDKEVVSMLASCNGLVEVVLRDCKHLTG 424

  Fly   490 KGLQTLAEDLTNLKTIDLYGCTQLSSKGID-IIMKLPKLQKL 530
            ..|..|.::...|||:|:.||..:....:: .:||...|:||
plant   425 AVLVALNKNCVKLKTLDILGCRLIEPDDVEGFVMKTQCLKKL 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	8/39 (21%)
		AMN1	<226..>334	CDD:187754	32/181 (18%)
		leucine-rich repeat	236..256	CDD:275381	8/51 (16%)
		leucine-rich repeat	263..288	CDD:275381	6/55 (11%)
		leucine-rich repeat	289..314	CDD:275381	8/25 (32%)
		leucine-rich repeat	315..347	CDD:275381	8/41 (20%)
		AMN1	347..524	CDD:187754	49/190 (26%)
		leucine-rich repeat	348..373	CDD:275381	8/24 (33%)
		leucine-rich repeat	374..398	CDD:275381	9/25 (36%)
		leucine-rich repeat	399..424	CDD:275381	8/24 (33%)
		leucine-rich repeat	425..450	CDD:275381	4/24 (17%)
		leucine-rich repeat	451..475	CDD:275381	5/24 (21%)
		leucine-rich repeat	476..501	CDD:275381	5/24 (21%)
AT5G40470	NP_198863.1	leucine-rich repeat	172..198	CDD:275381	4/25 (16%)
		leucine-rich repeat	199..222	CDD:275381	2/22 (9%)
		AMN1	<225..345	CDD:187754	32/124 (26%)
		leucine-rich repeat	229..250	CDD:275381	8/25 (32%)
		leucine-rich repeat	251..276	CDD:275381	6/24 (25%)
		leucine-rich repeat	277..303	CDD:275381	3/25 (12%)
		leucine-rich repeat	304..329	CDD:275381	8/24 (33%)
		leucine-rich repeat	330..384	CDD:275381	22/77 (29%)
		AMN1	<380..>448	CDD:187754	19/67 (28%)
		leucine-rich repeat	385..410	CDD:275381	5/24 (21%)
		leucine-rich repeat	411..436	CDD:275381	5/24 (21%)
		leucine-rich repeat	463..483	CDD:275381	3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810