DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and AT5G27920

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_568502.1	Gene:	AT5G27920 / 832858	AraportID:	AT5G27920	Length:	642	Species:	Arabidopsis thaliana

Alignment Length:	381	Identity:	99/381 - (25%)
Similarity:	169/381 - (44%)	Gaps:	94/381 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 TAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKVQILSLRRSLKDLVLGVPALTSLNL 241
            |.|.|.|             |:..||                ::||..|.:.|:       .:.|
plant   304 TIWIDGA-------------HVSDSS----------------LVSLSSSCRSLM-------EIGL 332

  Fly   242 SGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLL 306
            |.|.:|.|:.: .:.:.:..|||||:|:.|..:||.::..:||..|||.||:|..|..||..||.
plant   333 SRCVDVTDIGM-ISLARNCLNLKTLNLACCGFVTDVAISAVAQSCRNLGTLKLESCHLITEKGLQ 396

  Fly   307 LIAWGLKKLKHLNLRSCWHISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIA--- 368
            .:......::.|:|..|:.::|:|:.:::..|      |||...|||  |..:||:.:.||.
plant   397 SLGCYSMLVQELDLTDCYGVNDRGLEYISKCS------NLQRLKLGL--CTNISDKGIFHIGSKC 453

  Fly   369 ----------------QGLTSL----KSIN---LSFCVSVTDSGLKHLARMPKLEQLNLRSCDNI 410
                            .||.:|    ||:|   ||:|..:||:|::.:.::..|..|.||...||
plant   454 SKLLELDLYRCAGFGDDGLAALSRGCKSLNRLILSYCCELTDTGVEQIRQLELLSHLELRGLKNI 518

  Fly   411 SDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITDHGMLKIAKALHE 475
            :.:|:|.:..|...:..|||..|:.|.|.....:|.....||.::|..|.::|..:..:...|..
plant   519 TGVGLAAIASGCKKLGYLDVKLCENIDDSGFWALAYFSKNLRQINLCNCSVSDTALCMLMSNLSR 583

  Fly   476 LENLNIGQCSRITDKGLQ---------------------TLAEDLTNLKTIDLYGC 510
            ::::::...||:|.:|.:                     .|:.:|  |:|:...||
plant   584 VQDVDLVHLSRVTVEGFEFALRACCNRLKKLKLLAPLRFLLSSEL--LETLHARGC 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	4/12 (33%)
		AMN1	<226..>334	CDD:187754	33/107 (31%)
		leucine-rich repeat	236..256	CDD:275381	5/19 (26%)
		leucine-rich repeat	263..288	CDD:275381	10/24 (42%)
		leucine-rich repeat	289..314	CDD:275381	9/24 (38%)
		leucine-rich repeat	315..347	CDD:275381	7/31 (23%)
		AMN1	347..524	CDD:187754	53/211 (25%)
		leucine-rich repeat	348..373	CDD:275381	10/43 (23%)
		leucine-rich repeat	374..398	CDD:275381	10/30 (33%)
		leucine-rich repeat	399..424	CDD:275381	9/24 (38%)
		leucine-rich repeat	425..450	CDD:275381	7/24 (29%)
		leucine-rich repeat	451..475	CDD:275381	6/23 (26%)
		leucine-rich repeat	476..501	CDD:275381	6/45 (13%)
AT5G27920	NP_568502.1	AMN1	65..261	CDD:187754
		leucine-rich repeat	67..96	CDD:275381
		leucine-rich repeat	97..122	CDD:275381
		leucine-rich repeat	123..147	CDD:275381
		leucine-rich repeat	148..173	CDD:275381
		leucine-rich repeat	174..199	CDD:275381
		AMN1	192..393	CDD:187754	36/125 (29%)
		leucine-rich repeat	200..222	CDD:275381
		leucine-rich repeat	224..249	CDD:275381
		leucine-rich repeat	250..298	CDD:275381
		leucine-rich repeat	299..352	CDD:275381	16/84 (19%)
		AMN1	<329..464	CDD:187754	44/143 (31%)
		leucine-rich repeat	353..378	CDD:275381	10/24 (42%)
		leucine-rich repeat	379..404	CDD:275381	9/24 (38%)
		AMN1	405..>567	CDD:187754	48/169 (28%)
		leucine-rich repeat	405..429	CDD:275381	6/29 (21%)
		leucine-rich repeat	430..455	CDD:275381	10/26 (38%)
		leucine-rich repeat	456..481	CDD:275381	3/24 (13%)
		leucine-rich repeat	482..506	CDD:275381	7/23 (30%)
		leucine-rich repeat	507..532	CDD:275381	9/24 (38%)
		leucine-rich repeat	533..558	CDD:275381	7/24 (29%)
		leucine-rich repeat	559..583	CDD:275381	6/23 (26%)
		leucine-rich repeat	584..609	CDD:275381	4/24 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820