DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and SLOMO

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_567916.2	Gene:	SLOMO / 829457	AraportID:	AT4G33210	Length:	990	Species:	Arabidopsis thaliana

Alignment Length:	635	Identity:	132/635 - (20%)
Similarity:	213/635 - (33%)	Gaps:	240/635 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 HISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWK---------------------- 190
            || :|..:||..:|..|...||.|:|.||..||.|:..:..|:
plant   193 HI-DLTDDLLHMVFSFLNHVDLCRSAMVCRQWRVASAHEDFWRVLNFENIRISMEQFENMCSRYP 256

  Fly   191 --------GVEA---------------------KLHLKRS------------SPSLFNCLVKRGI 214
                    |..|                     |.|:..|            |.::.:.::..|.
plant   257 NATEVNVYGAPAVNALAMKAATTLRNLEVLTIGKGHISESFFQALGECNMLRSVTVSDAILGNGA 321

  Fly   215 KKVQI---------------------------LSLRRS-LKDLVLGVPALTSLNLSGCFNVADMN 251
            :::.:                           |||:|| :...:|..|.|..|:::.|..:.|..
plant   322 QEIHLSHDRLRELKITKCRVMRLSIRCPQLRSLSLKRSNMSQAMLNCPLLQLLDIASCHKLLDAA 386

  Fly   252 LGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQ---------------------HLRNLETLELG 295
            :..| ::..|.|::||:|.|..::|.:|..|||                     ||..|..|:|.
plant   387 IRSA-AISCPQLESLDVSNCSCVSDETLREIAQACANLHILNASYCPNISLESVHLPMLTVLKLH 450

  Fly   296 GCCNITNTGLLLIA--------------------WGLKKLKHLNLRSCWHISDQG---------- 330
            .|..||:..:..||                    ..|.:|:.::|..|...:|..
plant   451 SCEGITSASMTWIANSPALEVLELDNCNLLTTVSLHLSRLQSISLVHCRKFTDLNLQSIMLSSIT 515

  Fly   331 IGHLAGFSRETAEGN-----------------LQ---LEYLGLQDCQRLSDEALGHIAQ--GLTS 373
            :.:.....|.|...|                 ||   |:.:.|.||:.||:......:.  |...
plant   516 VSNCPALRRITITSNALRRLALQKQENLTTLVLQCHSLQEVDLSDCESLSNSVCKIFSDDGGCPM 580

  Fly   374 LKSINLSFCVSVT-----DSGLKHLA------------RMPKLEQLNLRSCDNIS---------- 411
            |||:.|..|.|:|     :|.|..|:            :.|::||:.|..||::.
plant   581 LKSLILDNCESLTAVRFCNSSLASLSLVGCRAVTSLELKCPRIEQICLDGCDHLETAFFQPVALR 645

  Fly   412 --DIG--------------MAYLTEGGSGI-----------NSLDVSFCDKISDQALTHIAQGLY 449
              ::|              |..|...|.|:           .|||.|||.::.|..|:.......
plant   646 SLNLGICPKLSVLNIEAPYMVSLELKGCGVLSEASIMCPLLTSLDASFCSQLRDDCLSATTASCP 710

  Fly   450 RLRSLSLNQC-QITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQL 513
            .:.||.|..| .|...|:    .:|:.|.||.:...|......|:.:.:....||.:.|..|..|
plant   711 LIESLVLMSCPSIGSDGL----SSLNGLPNLTVLDLSYTFLMNLEPVFKSCIQLKVLKLQACKYL 771

  Fly   514 SSKGIDIIMK---LPKLQKLNLGLW---------LVRXCVH--H-DCNAC 548
            :...::.:.|   ||.|::|:|...         |:..|.|  | ..|.|
plant   772 TDSSLEPLYKEGALPALEELDLSYGTLCQTAIDDLLACCTHLTHLSLNGC 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	15/40 (38%)
		AMN1	<226..>334	CDD:187754	33/158 (21%)
		leucine-rich repeat	236..256	CDD:275381	4/19 (21%)
		leucine-rich repeat	263..288	CDD:275381	12/45 (27%)
		leucine-rich repeat	289..314	CDD:275381	9/44 (20%)
		leucine-rich repeat	315..347	CDD:275381	7/58 (12%)
		AMN1	347..524	CDD:187754	55/239 (23%)
		leucine-rich repeat	348..373	CDD:275381	7/26 (27%)
		leucine-rich repeat	374..398	CDD:275381	10/40 (25%)
		leucine-rich repeat	399..424	CDD:275381	9/50 (18%)
		leucine-rich repeat	425..450	CDD:275381	8/35 (23%)
		leucine-rich repeat	451..475	CDD:275381	7/24 (29%)
		leucine-rich repeat	476..501	CDD:275381	5/24 (21%)
SLOMO	NP_567916.2	F-box-like	195..234	CDD:372399	14/38 (37%)
		leucine-rich repeat	208..257	CDD:275381	11/48 (23%)
		leucine-rich repeat	258..282	CDD:275381	2/23 (9%)
		leucine-rich repeat	283..306	CDD:275381	3/22 (14%)
		leucine-rich repeat	307..326	CDD:275381	2/18 (11%)
		leucine-rich repeat	331..350	CDD:275381	0/18 (0%)
		AMN1	344..523	CDD:187754	38/179 (21%)
		leucine-rich repeat	371..396	CDD:275381	5/25 (20%)
		leucine-rich repeat	397..422	CDD:275381	10/24 (42%)
		leucine-rich repeat	423..443	CDD:275381	2/19 (11%)
		leucine-rich repeat	444..468	CDD:275381	8/23 (35%)
		leucine-rich repeat	469..489	CDD:275381	1/19 (5%)
		leucine-rich repeat	490..521	CDD:275381	4/30 (13%)
		AMN1	<516..660	CDD:187754	29/143 (20%)
		leucine-rich repeat	522..552	CDD:275381	5/29 (17%)
		leucine-rich repeat	602..622	CDD:275381	2/19 (11%)
		leucine-rich repeat	623..643	CDD:275381	5/19 (26%)
		leucine-rich repeat	644..664	CDD:275381	1/19 (5%)
		AMN1	682..>826	CDD:187754	37/144 (26%)
		leucine-rich repeat	686..711	CDD:275381	8/24 (33%)
		leucine-rich repeat	712..731	CDD:275381	6/22 (27%)
		leucine-rich repeat	737..759	CDD:275381	3/21 (14%)
		leucine-rich repeat	760..787	CDD:275381	7/26 (27%)
		leucine-rich repeat	788..812	CDD:275381	5/23 (22%)
		leucine-rich repeat	906..951	CDD:275381
		leucine-rich repeat	952..977	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820