DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and AFB4

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_567702.2	Gene:	AFB4 / 828541	AraportID:	AT4G24390	Length:	623	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	108/500 - (21%)
Similarity:	192/500 - (38%)	Gaps:	125/500 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LYLQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPESPPPVEGTHISNLFPELLEQIFEHLPV 166
            |.|....::::::::||.......:.          ..||||.....:.|    :||.:.:.|..
plant    18 LNLNPPCSSSSSSSSAATFTNKSRNF----------KSSPPPCPDHVLEN----VLENVLQFLTS 68

  Fly   167 R-DLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLF--NCLVKRGIKKVQILSLRRSLKD 228
            | |....:.||.:|    |.      |||:..|:     :|  ||.   .:...:::...:.::.
plant    69 RCDRNAVSLVCRSW----YR------VEAQTRLE-----VFIGNCY---SLSPARLIHRFKRVRS 115

  Fly   229 LVL-GVPALTSLNLSGCFNVADMNLGHAFS------------VDLPNLKTLDLSLCKQITDTSLG 280
            ||| |.|....      ||:...|.|..||            ::..:||.:      .:||..|.
plant   116 LVLKGKPRFAD------FNLMPPNWGAQFSPWVAATAKAYPWLEKVHLKRM------FVTDDDLA 168

  Fly   281 RIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHLAGFSRETAEGN 345
            .:|:.....:.|.|..|.....:|:.::|...::||.|:|... .::|..:..::.|    .||.
plant   169 LLAESFPGFKELTLVCCEGFGTSGIAIVANKCRQLKVLDLMES-EVTDDELDWISCF----PEGE 228

  Fly   346 LQLEYLGLQDC--QRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLARMPKLEQLN----- 403
            ..||.|.. ||  ..::.:||..:......||.:..:..||:.:.. :.:.|.|:|..|.
plant   229 THLESLSF-DCVESPINFKALEELVVRSPFLKKLRTNRFVSLEELH-RLMVRAPQLTSLGTGSFS 291

  Fly   404 ----------------LRSCDNI------SDIGMAYLTEGGS---GINSLDVSFCDKISDQALTH 443
                            .|:|.:|      .:....||....|   .:.||:.|:.: ||...|..
plant   292 PDNVPQGEQQPDYAAAFRACKSIVCLSGFREFRPEYLLAISSVCANLTSLNFSYAN-ISPHMLKP 355

  Fly   444 IAQGLYRLRSL-SLNQCQITDHGMLKIAKALHELENLNI----------GQCSRITDKGLQTLAE 497
            |....:.:|.. :|:  .|.|.|:..:|....||..|.|          |..|.:   |||.::|
plant   356 IISNCHNIRVFWALD--SIRDEGLQAVAATCKELRELRIFPFDPREDSEGPVSGV---GLQAISE 415

  Fly   498 DLTNLKTIDLYGCTQLSSKGIDIIMK-LPKLQKLNLGLWLVRXCV 541
            ....|::| ||.|..:::..:..:.: .|:|.       :.| |:
plant   416 GCRKLESI-LYFCQNMTNGAVTAMSENCPQLT-------VFRLCI 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	10/41 (24%)
		AMN1	<226..>334	CDD:187754	27/120 (23%)
		leucine-rich repeat	236..256	CDD:275381	4/19 (21%)
		leucine-rich repeat	263..288	CDD:275381	6/24 (25%)
		leucine-rich repeat	289..314	CDD:275381	5/24 (21%)
		leucine-rich repeat	315..347	CDD:275381	8/31 (26%)
		AMN1	347..524	CDD:187754	49/220 (22%)
		leucine-rich repeat	348..373	CDD:275381	7/26 (27%)
		leucine-rich repeat	374..398	CDD:275381	5/23 (22%)
		leucine-rich repeat	399..424	CDD:275381	8/54 (15%)
		leucine-rich repeat	425..450	CDD:275381	7/24 (29%)
		leucine-rich repeat	451..475	CDD:275381	6/24 (25%)
		leucine-rich repeat	476..501	CDD:275381	9/34 (26%)
AFB4	NP_567702.2	F-box_5	51..90	CDD:375937	13/52 (25%)
		Transp_inhibit	112..157	CDD:376210	11/50 (22%)
		leucine-rich repeat	152..176	CDD:275381	6/29 (21%)
		AMN1	<162..>283	CDD:187754	30/127 (24%)
		leucine-rich repeat	177..202	CDD:275381	5/24 (21%)
		leucine-rich repeat	203..257	CDD:275381	15/59 (25%)
		leucine-rich repeat	258..330	CDD:275381	13/72 (18%)
		leucine-rich repeat	338..362	CDD:275381	7/24 (29%)
		leucine-rich repeat	363..386	CDD:275381	6/24 (25%)
		AMN1	<384..538	CDD:187754	19/79 (24%)
		leucine-rich repeat	387..419	CDD:275381	9/34 (26%)
		leucine-rich repeat	420..444	CDD:275381	5/24 (21%)
		leucine-rich repeat	445..479	CDD:275381	3/14 (21%)
		leucine-rich repeat	480..503	CDD:275381
		leucine-rich repeat	504..528	CDD:275381
		leucine-rich repeat	529..553	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820