DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and AT4G23840

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_194115.3	Gene:	AT4G23840 / 828483	AraportID:	AT4G23840	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	121/468 - (25%)
Similarity:	199/468 - (42%)	Gaps:	106/468 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 SPESPPPVEGTHISN-----------LFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWK 190
            |.||.||    |:::           |||.|||.....:...||...:.|...|  .||...
plant    29 SLESLPP----HLADALLRRLLKKRLLFPSLLEGFKYSVENIDLRGKSSVNAEW--MAYIGG--- 84

  Fly   191 GVEAKLHLKRSSPSLFNCLVKRGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHA 255
                           |..|:...:...|  .:..|....:.|:.:||.|:||.||.|.|..:.|.
plant    85 ---------------FVNLITLNLSDCQ--RINSSTLWPITGLTSLTELDLSRCFKVTDAGMKHL 132

  Fly   256 FSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNL 320
            .||  .|||.|.:|. ..:|:..:..:|. |:.|..|:||| ..:|:..|:.:. .|.||::|::
plant   133 QSV--VNLKKLWISQ-TGVTEVGISLLAS-LKKLSLLDLGG-LPVTDQNLISLQ-ALTKLEYLDI 191

  Fly   321 RSCW--HISDQGIGHLAGFSR----------ETAEGNL-QLEYLGLQDCQRLSDEALGHIAQGLT 372
               |  ::::||...:..||.          .|...|: .||.|.:..|..:| |...|  ..|.
plant   192 ---WGSNVTNQGAVSILKFSNLSFLNLSWTSITQTPNIPHLECLHMNTCTIVS-EPKTH--SSLA 250

  Fly   373 SLKSI------------NLSF----CVS---VTDSGLKH---LARMPKLEQLNLRSCDNISDIGM 415
            |||.:            :|||    |::   |:.:.||:   |..|..||.|:| |.....|..:
plant   251 SLKKLVLSGANFSAETESLSFTNKSCITYLDVSKTSLKNFSFLETMFNLEHLDL-SSTAFGDDSV 314

  Fly   416 AYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITDHGMLKIAKALHELENLN 480
            .::...|..:.:|:|| ..:|:...:.::|..:.:|.:||::|..:.|..:|.|:..:..::.|:
plant   315 GFVACVGENLKNLNVS-DTQITPSGVGNLAGHVPQLETLSMSQTFVDDLSILLISTTMPCIKALD 378

  Fly   481 IGQCSRI-----------TDKGLQTLAEDLTNLKTIDL---YGCTQLSSKGIDIIMKLPKLQKLN 531
            :|..|.:           .:|.|..| :.||:|:|:.|   |    |..|.:..:..|..|..|:
plant   379 LGMNSTLGFYYLISPQEEKEKSLAAL-QSLTSLETLSLEHPY----LGDKALSGLSSLTGLTHLS 438

  Fly   532 L-GLWLVRXCVHH 543
            | ...|.. .:||
plant   439 LTSTSLTDSTLHH 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	12/51 (24%)
		AMN1	<226..>334	CDD:187754	35/109 (32%)
		leucine-rich repeat	236..256	CDD:275381	10/19 (53%)
		leucine-rich repeat	263..288	CDD:275381	7/24 (29%)
		leucine-rich repeat	289..314	CDD:275381	8/24 (33%)
		leucine-rich repeat	315..347	CDD:275381	9/44 (20%)
		AMN1	347..524	CDD:187754	53/212 (25%)
		leucine-rich repeat	348..373	CDD:275381	8/24 (33%)
		leucine-rich repeat	374..398	CDD:275381	11/45 (24%)
		leucine-rich repeat	399..424	CDD:275381	7/24 (29%)
		leucine-rich repeat	425..450	CDD:275381	5/24 (21%)
		leucine-rich repeat	451..475	CDD:275381	7/23 (30%)
		leucine-rich repeat	476..501	CDD:275381	7/35 (20%)
AT4G23840	NP_194115.3	AMN1	85..>238	CDD:187754	46/163 (28%)
		leucine-rich repeat	88..112	CDD:275381	4/25 (16%)
		leucine-rich repeat	113..137	CDD:275381	12/25 (48%)
		leucine-rich repeat	138..185	CDD:275381	15/50 (30%)
		leucine-rich repeat	186..209	CDD:275381	6/25 (24%)
		leucine-rich repeat	210..248	CDD:275381	9/40 (23%)
		leucine-rich repeat	252..273	CDD:275380	5/20 (25%)
		LRR_RI	<291..490	CDD:238064	42/168 (25%)
		leucine-rich repeat	299..323	CDD:275381	7/24 (29%)
		leucine-rich repeat	324..348	CDD:275381	5/24 (21%)
		leucine-rich repeat	349..373	CDD:275381	7/23 (30%)
		leucine-rich repeat	374..409	CDD:275381	7/35 (20%)
		leucine-rich repeat	410..433	CDD:275381	7/26 (27%)
		leucine-rich repeat	434..457	CDD:275381	6/18 (33%)
		leucine-rich repeat	458..481	CDD:275381
		leucine-rich repeat	482..507	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010