DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and GRH1

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_567255.1	Gene:	GRH1 / 828045	AraportID:	AT4G03190	Length:	585	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	112/512 - (21%)
Similarity:	187/512 - (36%)	Gaps:	159/512 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 PELLEQIFEHLPV-RDLGRAAQVCTAW--RDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIK 215
            |::||.|...:.. .|....:.||.:|  .:....|.|:.|               ||..
plant     7 PKVLEHILSFIDSNEDRNSVSLVCKSWFETERKTRKRVFVG---------------NCYA----- 51

  Fly   216 KVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNL------GHAFS-VDLPNLKTLDLSLCKQ 273
             |...::.|..       |.:.||.|.|..:.||.||      |:|:. ::....|:..|...:.
plant    52 -VSPAAVTRRF-------PEMRSLTLKGKPHFADYNLVPDGWGGYAWPWIEAMAAKSSSLEEIRM 108

  Fly   274 ----ITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHL 334
                :||..|.:||...::.:.|.|..|...:..|:..||...:.|:.|.||.| .:.|.| |..
plant   109 KRMVVTDECLEKIAASFKDFKVLVLTSCEGFSTDGIAAIAATCRNLRVLELREC-IVEDLG-GDW 171

  Fly   335 AGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLAR-MPK 398
            ..:..|::...:.|::..|....::||  |..:.....:|||:.|:  .:||..||..|.| .|:
plant   172 LSYFPESSTSLVSLDFSCLDSEVKISD--LERLVSRSPNLKSLKLN--PAVTLDGLVSLLRCAPQ 232

  Fly   399 LEQL-------------------------NLRSCDNISDIGMAYLTEGGS---GINSLDVSF--- 432
            |.:|                         .|:|...:.|:...||....|   |:.||::|:
plant   233 LTELGTGSFAAQLKPEAFSKLSEAFSNCKQLQSLSGLWDVLPEYLPALYSVCPGLTSLNLSYATV 297

  Fly   433 -----------CDK---------ISDQALTHIAQGLYRLRSLSL---------NQCQITDHGMLK 468
                       |.|         |.|:.|..:|.....||.|.:         ....:|:.|::.
plant   298 RMPDLVELLRRCSKLQKLWVMDLIEDKGLEAVASYCKELRELRVFPSEPDLDATNIPLTEQGLVF 362

  Fly   469 IAKALHELENL--------------------NIGQCSRI---------------TDKGLQTLAED 498
            ::|...:||::                    |: :|.|:               .|||.:.:||.
plant   363 VSKGCRKLESVLYFCVQFTNAALFTIARKRPNL-KCFRLCVIEPFAPDYKTNEPLDKGFKAIAEG 426

  Fly   499 LTNLKTIDLYGCTQLSSKGIDIIMK-LPKLQKLNLG------LWLVRXCVHHDCNAC 548
            ..:|:.:.:.|.  ||.|....|.| ..|::.|::.      |.|     ||..:.|
plant   427 CRDLRRLSVSGL--LSDKAFKYIGKHAKKVRMLSIAFAGDSDLML-----HHLLSGC 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	10/38 (26%)
		AMN1	<226..>334	CDD:187754	32/118 (27%)
		leucine-rich repeat	236..256	CDD:275381	9/25 (36%)
		leucine-rich repeat	263..288	CDD:275381	7/28 (25%)
		leucine-rich repeat	289..314	CDD:275381	6/24 (25%)
		leucine-rich repeat	315..347	CDD:275381	9/31 (29%)
		AMN1	347..524	CDD:187754	57/273 (21%)
		leucine-rich repeat	348..373	CDD:275381	5/24 (21%)
		leucine-rich repeat	374..398	CDD:275381	10/24 (42%)
		leucine-rich repeat	399..424	CDD:275381	8/52 (15%)
		leucine-rich repeat	425..450	CDD:275381	9/47 (19%)
		leucine-rich repeat	451..475	CDD:275381	6/32 (19%)
		leucine-rich repeat	476..501	CDD:275381	10/59 (17%)
GRH1	NP_567255.1	F-box_5	4..43	CDD:408301	8/35 (23%)
		Transp_inhibit	62..108	CDD:408562	13/45 (29%)
		leucine-rich repeat	103..127	CDD:275381	6/23 (26%)
		AMN1	<112..267	CDD:187754	40/160 (25%)
		leucine-rich repeat	128..153	CDD:275381	6/24 (25%)
		leucine-rich repeat	154..208	CDD:275381	14/57 (25%)
		leucine-rich repeat	209..232	CDD:275381	10/24 (42%)
		leucine-rich repeat	233..279	CDD:275381	7/45 (16%)
		AMN1	280..488	CDD:187754	41/205 (20%)
		leucine-rich repeat	287..311	CDD:275381	4/23 (17%)
		leucine-rich repeat	312..335	CDD:275381	4/22 (18%)
		leucine-rich repeat	336..369	CDD:275381	6/32 (19%)
		leucine-rich repeat	370..394	CDD:275381	2/23 (9%)
		leucine-rich repeat	395..429	CDD:275381	7/34 (21%)
		leucine-rich repeat	430..453	CDD:275381	7/24 (29%)
		leucine-rich repeat	454..478	CDD:275381	6/28 (21%)
		leucine-rich repeat	479..498	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820