DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and AT4G15475

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_567467.1	Gene:	AT4G15475 / 827219	AraportID:	AT4G15475	Length:	610	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	134/594 - (22%)
Similarity:	210/594 - (35%)	Gaps:	214/594 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 ISNLFP-ELLEQIFEHL---PVRDLGRAAQVCTAW---------------------------RDA 182
            |:|..| ||:.:||..|   |.||  ..:.||..|                           |..
plant     7 INNCLPEELILEIFRRLESKPNRD--ACSLVCKRWLSLERFSRTTLRIGASFSPDDFISLLSRRF 69

  Fly   183 AYAKSVWKGVEAKLHLKRSSPSLFNCLVKR-----------------------GIKKVQILSLR- 223
            .|..|:.......:.|...|||     .||                       |.:.|:..||.
plant    70 LYITSIHVDERISVSLPSLSPS-----PKRKRGRDSSSPSSSKRKKLTDKTHSGAENVESSSLTD 129

  Fly   224 RSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDL--------------SLCKQ- 273
            ..|..|..|.|.:.:|:|..|.||:.:.| .:.:....:||:|||              ..|||
plant   130 TGLTALANGFPRIENLSLIWCPNVSSVGL-CSLAQKCTSLKSLDLQGCYVGDQGLAAVGKFCKQL 193

  Fly   274 -------------------------------------ITDTSLGRIAQHLRNLETLELG------ 295
                                                 |||.||..:..|.:.||.|.|.
plant   194 EELNLRFCEGLTDVGVIDLVVGCSKSLKSIGVAASAKITDLSLEAVGSHCKLLEVLYLDSEYIHD 258

  Fly   296 --------GC------------------------C------------NITNTGLLLIAWGLKKLK 316
                    ||                        |            :.|:.|:..|..|.||||
plant   259 KGLIAVAQGCHRLKNLKLQCVSVTDVAFAAVGELCTSLERLALYSFQHFTDKGMRAIGKGSKKLK 323

  Fly   317 HLNLRSCWHISDQGIGHLA-------------------------------------------GFS 338
            .|.|..|:.:|.:|:..:|                                           |.|
plant   324 DLTLSDCYFVSCKGLEAIAHGCKELERVEINGCHNIGTRGIEAIGKSCPRLKELALLYCQRIGNS 388

  Fly   339 --RETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLARMPK-LE 400
              :|..:|...||.|.|.||..:.|.|:..||:|..:||.:::..|..:.:.|:..:.:..| |.
plant   389 ALQEIGKGCKSLEILHLVDCSGIGDIAMCSIAKGCRNLKKLHIRRCYEIGNKGIISIGKHCKSLT 453

  Fly   401 QLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQ-ITDH 464
            :|:||.||.:.:..:..:.:|.| :..|:||.|::|||..:|.||:|..:|..|.::..| |.|.
plant   454 ELSLRFCDKVGNKALIAIGKGCS-LQQLNVSGCNQISDAGITAIARGCPQLTHLDISVLQNIGDM 517

  Fly   465 GMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGI-DIIMKLPKLQ 528
            .:.::.:....|::|.:..|..|||.||..|.:....|:|..:..|..::|.|: .::...|.::
plant   518 PLAELGEGCPMLKDLVLSHCHHITDNGLNHLVQKCKLLETCHMVYCPGITSAGVATVVSSCPHIK 582

  Fly   529 KLNLGLWLV 537
            |:.:..|.|
plant   583 KVLIEKWKV 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	17/71 (24%)
		AMN1	<226..>334	CDD:187754	44/209 (21%)
		leucine-rich repeat	236..256	CDD:275381	6/19 (32%)
		leucine-rich repeat	263..288	CDD:275381	14/76 (18%)
		leucine-rich repeat	289..314	CDD:275381	11/74 (15%)
		leucine-rich repeat	315..347	CDD:275381	12/76 (16%)
		AMN1	347..524	CDD:187754	54/179 (30%)
		leucine-rich repeat	348..373	CDD:275381	11/24 (46%)
		leucine-rich repeat	374..398	CDD:275381	4/23 (17%)
		leucine-rich repeat	399..424	CDD:275381	7/24 (29%)
		leucine-rich repeat	425..450	CDD:275381	11/24 (46%)
		leucine-rich repeat	451..475	CDD:275381	5/24 (21%)
		leucine-rich repeat	476..501	CDD:275381	9/24 (38%)
AT4G15475	NP_567467.1	FBOX	11..>42	CDD:197608	12/32 (38%)
		leucine-rich repeat	142..167	CDD:275381	6/25 (24%)
		leucine-rich repeat	168..192	CDD:275381	6/23 (26%)
		AMN1	190..359	CDD:187754	30/168 (18%)
		leucine-rich repeat	193..218	CDD:275381	0/24 (0%)
		leucine-rich repeat	220..245	CDD:275381	6/24 (25%)
		leucine-rich repeat	246..263	CDD:275381	4/16 (25%)
		leucine-rich repeat	271..295	CDD:275381	1/23 (4%)
		leucine-rich repeat	296..321	CDD:275381	4/24 (17%)
		leucine-rich repeat	322..347	CDD:275381	8/24 (33%)
		AMN1	<345..514	CDD:187754	42/169 (25%)
		leucine-rich repeat	348..369	CDD:275381	0/20 (0%)
		leucine-rich repeat	374..399	CDD:275381	4/24 (17%)
		leucine-rich repeat	400..425	CDD:275381	11/24 (46%)
		leucine-rich repeat	426..451	CDD:275381	4/24 (17%)
		AMN1	<448..586	CDD:187754	41/138 (30%)
		leucine-rich repeat	452..476	CDD:275381	7/23 (30%)
		leucine-rich repeat	477..502	CDD:275381	11/24 (46%)
		leucine-rich repeat	503..528	CDD:275381	5/24 (21%)
		leucine-rich repeat	529..554	CDD:275381	9/24 (38%)
		leucine-rich repeat	555..580	CDD:275381	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820