DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and ARABIDILLO-2

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001319805.1	Gene:	ARABIDILLO-2 / 825206	AraportID:	AT3G60350	Length:	928	Species:	Arabidopsis thaliana

Alignment Length:	463	Identity:	96/463 - (20%)
Similarity:	181/463 - (39%)	Gaps:	114/463 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 IFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLH---LKRSSPSLFNCLVKRGIKKVQILS 221
            :|..|..||....|..|..||....:..:|..::.:.|   |..::.....|:   .::|::...
plant    51 LFTRLNYRDRASLASTCRTWRSLGASSFLWSSLDLRAHKFDLSMAASLATRCV---DLQKIRFRG 112

  Fly   222 LRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHL 286
            :..:  |.::.:.|.:.|.:||.:                         |::|||.:|..||...
plant   113 VDSA--DAIIHLKARSLLEISGDY-------------------------CRKITDATLSMIAARH 150

  Fly   287 RNLETLELGG--CCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHLAGFSRETAEGNLQLE 349
            ..||:|:||.  |..||:..:.:||:...|||.|.:.....:|.:.|..||....       ||.
plant   151 EALESLQLGPDFCERITSDAIRVIAFCCPKLKKLRVSGMRDVSSEAIESLAKHCP-------QLS 208

  Fly   350 YLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVT-DSGLKHLARMPKLEQLNLRSCDNISDI 413
            .||..||..:::||||.:    .||:.::::...::. ...|::..::|||..|:: |...|..|
plant   209 DLGFLDCLNINEEALGKV----VSLRYLSVAGTSNIKWKVALENWEKLPKLIGLDV-SRTTIDHI 268

  Fly   414 GMAYLTEGGSGINSLDVSFCDKIS-----------------------DQALTHIAQGLYRLRSL- 454
            .::.|.:....:..|....|..:.                       |:..:..|....:.:::
plant   269 AVSRLLKSSQSLKVLCALNCPYLEEDKSYSSNRFKGKVLLAVFTDTFDELASIFADNSKKPKNIF 333

  Fly   455 -----------SLNQCQ-----ITDHGMLKIAKALHELENLN---IGQCSRITDKGLQTLAEDL- 499
                       |:::..     |..|.:|:||::.:. :.||   :.|.:.:....:|:..||:
plant   334 SYWRDLIRKDKSIDEIMLWIEWIISHTLLRIAESSNS-QGLNDFWLNQGATLLLSLMQSAQEDVQ 397

  Fly   500 ----TNLKT----------IDLYGCTQ----LSSKGIDIIMKLPKLQKLNLGLWLVRXCVHHDCN 546
                |.|.|          ||   |.:    :...||.::::|.|..:..|.....: ..:...|
plant   398 ERAATGLATFIVVDDENASID---CGRAEAVMRDGGIRLLLELAKSWREGLQSEAAKAIANLSVN 459

  Fly   547 ACAAKEAA 554
            |..||..|
plant   460 AKVAKAVA 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	8/29 (28%)
		AMN1	<226..>334	CDD:187754	28/109 (26%)
		leucine-rich repeat	236..256	CDD:275381	3/19 (16%)
		leucine-rich repeat	263..288	CDD:275381	7/24 (29%)
		leucine-rich repeat	289..314	CDD:275381	10/26 (38%)
		leucine-rich repeat	315..347	CDD:275381	7/31 (23%)
		AMN1	347..524	CDD:187754	45/239 (19%)
		leucine-rich repeat	348..373	CDD:275381	9/24 (38%)
		leucine-rich repeat	374..398	CDD:275381	2/24 (8%)
		leucine-rich repeat	399..424	CDD:275381	6/24 (25%)
		leucine-rich repeat	425..450	CDD:275381	4/47 (9%)
		leucine-rich repeat	451..475	CDD:275381	6/40 (15%)
		leucine-rich repeat	476..501	CDD:275381	6/32 (19%)
ARABIDILLO-2	NP_001319805.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910