DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and EBF1

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_565597.1	Gene:	EBF1 / 817087	AraportID:	AT2G25490	Length:	628	Species:	Arabidopsis thaliana

Alignment Length:	395	Identity:	107/395 - (27%)
Similarity:	180/395 - (45%)	Gaps:	64/395 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 GVEAKLHLKRS-----SPSLFNC-LVK-RGIK-------------KVQILSLR-----------R 224
            |.|..|.:.||     |.|:.|| ||: :||.             |:|:|::.           .
plant   243 GDEGLLAIARSCSKLKSVSIKNCPLVRDQGIASLLSNTTCSLAKLKLQMLNVTDVSLAVVGHYGL 307

  Fly   225 SLKDLVL------------------GVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLC 271
            |:.||||                  |:..|.||.::.|..|.||.| .:.....||:|...:|..
plant   308 SITDLVLAGLSHVSEKGFWVMGNGVGLQKLNSLTITACQGVTDMGL-ESVGKGCPNMKKAIISKS 371

  Fly   272 KQITDTSLGRIAQHLRNLETLELGGCCNITNTGLL--LIAWGLKKLKHLNLRSCWHISDQGIGHL 334
            ..::|..|...|:...:||:|:|..|..:|..|..  |:..| :|||..:|.:|..|.|...| |
plant   372 PLLSDNGLVSFAKASLSLESLQLEECHRVTQFGFFGSLLNCG-EKLKAFSLVNCLSIRDLTTG-L 434

  Fly   335 AGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLARMPKL 399
            ...|..:|     |..|.:::|....|..|..|.:....|:.|:|.....:|:||..||.: ..|
plant   435 PASSHCSA-----LRSLSIRNCPGFGDANLAAIGKLCPQLEDIDLCGLKGITESGFLHLIQ-SSL 493

  Fly   400 EQLNLRSCDNISDIGMAYLT-EGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITD 463
            .::|...|.|::|..::.:| ..|..:..|::..|..|:|.:|..||.....|..|.:::|.|:|
plant   494 VKINFSGCSNLTDRVISAITARNGWTLEVLNIDGCSNITDASLVSIAANCQILSDLDISKCAISD 558

  Fly   464 HGMLKIAKA-LHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKL 527
            .|:..:|.: ..:|:.|::..||.:|||.|..:....:.|..::|..|..:|:..:|.:::  :|
plant   559 SGIQALASSDKLKLQILSVAGCSMVTDKSLPAIVGLGSTLLGLNLQQCRSISNSTVDFLVE--RL 621

  Fly   528 QKLNL 532
            .|.::
plant   622 YKCDI 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689
		AMN1	<226..>334	CDD:187754	37/127 (29%)
		leucine-rich repeat	236..256	CDD:275381	8/19 (42%)
		leucine-rich repeat	263..288	CDD:275381	5/24 (21%)
		leucine-rich repeat	289..314	CDD:275381	9/26 (35%)
		leucine-rich repeat	315..347	CDD:275381	10/31 (32%)
		AMN1	347..524	CDD:187754	48/178 (27%)
		leucine-rich repeat	348..373	CDD:275381	6/24 (25%)
		leucine-rich repeat	374..398	CDD:275381	8/23 (35%)
		leucine-rich repeat	399..424	CDD:275381	7/25 (28%)
		leucine-rich repeat	425..450	CDD:275381	7/24 (29%)
		leucine-rich repeat	451..475	CDD:275381	7/24 (29%)
		leucine-rich repeat	476..501	CDD:275381	8/24 (33%)
EBF1	NP_565597.1	F-box-like	64..101	CDD:372399
		AMN1	<149..298	CDD:187754	16/54 (30%)
		leucine-rich repeat	179..204	CDD:275381
		leucine-rich repeat	205..230	CDD:275381
		leucine-rich repeat	231..256	CDD:275381	5/12 (42%)
		leucine-rich repeat	257..283	CDD:275381	8/25 (32%)
		leucine-rich repeat	284..308	CDD:275381	3/23 (13%)
		leucine-rich repeat	309..336	CDD:275381	5/26 (19%)
		leucine-rich repeat	337..362	CDD:275381	8/25 (32%)
		leucine-rich repeat	363..388	CDD:275381	5/24 (21%)
		leucine-rich repeat	416..442	CDD:275381	9/26 (35%)
		AMN1	440..611	CDD:187754	47/176 (27%)
		leucine-rich repeat	443..468	CDD:275381	6/24 (25%)
		leucine-rich repeat	469..492	CDD:275381	8/23 (35%)
		leucine-rich repeat	493..519	CDD:275381	7/25 (28%)
		leucine-rich repeat	520..545	CDD:275381	7/24 (29%)
		leucine-rich repeat	546..571	CDD:275381	7/24 (29%)
		leucine-rich repeat	572..591	CDD:275381	8/18 (44%)
		leucine-rich repeat	598..619	CDD:275381	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820