DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and AT2G17020

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_565400.1	Gene:	AT2G17020 / 816205	AraportID:	AT2G17020	Length:	656	Species:	Arabidopsis thaliana

Alignment Length:	579	Identity:	144/579 - (24%)
Similarity:	219/579 - (37%)	Gaps:	192/579 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 EGTHISNLFP-ELLEQIFEHLPVRDLGRAAQVCTAWRDAA----------YAKSVWKGVEA---- 194
            :|....:|.| .|||.|...|.|..|...|..|...:...          :..:|...:|.
plant    18 DGERSLDLLPAALLETIMTKLDVASLCSLASTCKTLKSCVTRVLTFTPNFHIFNVSLSMETVRPL 82

  Fly   195 ----------KLHLKRSSPSLFNCLVKRGIKKVQILSLR-----------RSLKD---LVLGVP- 234
                      ||...|...|..:.||:..::::.:.:.|           |..||   |.||..
plant    83 LFPNQQLSSLKLDCGRLGNSAIDILVRPSLREISLHNCRDFSGDLISEIGRKCKDLRLLCLGSVA 147

  Fly   235 ----------ALTSLNLSGCFN------------------------VAD----MNLGH------- 254
                      ||..| |:||.:                        |:|    :.|||
plant   148 EKVGRSISRCALEDL-LNGCSHLEVLALMFDLSLYLRPGDGRIFGLVSDRLTHLELGHITSRMMT 211

  Fly   255 ----------------AFSVDLPNLKTLDLSL-CKQITDTSLGRIAQHLRNLETLELGGC----- 297
                            ..|..|.|::.|.||: |  |||..:..|::.|.:|..|::...
plant   212 QLLTSTEISGQDSNRVTTSTVLQNVQRLRLSVDC--ITDAVVKAISKSLPSLIDLDIRDAPLEDP 274

  Fly   298 ---CNITNTGLLLIAWGLKKLKHLNL-RSC-WH------ISDQGIGHLA------------GFSR 339
               .::|:.||..|... .|||||:| ||. :|      :||||:..||            ||.|
plant   275 RQVSDLTDFGLHEINQN-GKLKHLSLIRSQEFHPTYFRRVSDQGMLFLADKCLGMETICLGGFCR 338

  Fly   340 ETAEG---------------------------------NLQLEYLGLQDCQRLSDEALGHIAQGL 371
            .|..|                                 .|.|.::.|:.|..|:|.|:..:|..|
plant   339 VTDAGFKTILHSCASLSKFSIYHGPKLTDLVFHDILATTLSLSHVSLRRCHLLTDHAIQKLASSL 403

  Fly   372 TSLKSINLSFCVSVTDSGLKHLARMPKLEQLNLRSCDNISDIGMAYLTEGG-SGINSLDVSFCDK 435
             .|::::|..|.::.|..|..::.:|||:.|.|...| |||.|::||.||. ..:.||.|..|..
plant   404 -KLENLDLRGCRNLRDETLTAVSHLPKLKVLLLDGAD-ISDTGLSYLKEGVLDSLVSLSVRGCRN 466

  Fly   436 ISDQALTHIAQGLYR--LRSLSL-NQCQITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLA- 496
            ::|:.::.:..|..:  ||.|.| |...:||..:..:||:...:..|.:.:|..|.|..:..||
plant   467 LTDKFMSTLFDGSSKLALRELDLSNLPNLTDAAIFALAKSGAPITKLQLRECRLIGDASVMALAS 531

  Fly   497 ----EDL---TNLKTIDLYGC---TQLSSKGIDIIMKLPKLQKLNLGLWL-VRXCVHHD 544
                ||.   ::|..:|||.|   ||||.|.    :|.|...:|.   || :. .|:.|
plant   532 TRVYEDECPGSSLCLLDLYDCGGITQLSFKW----LKKPFFPRLK---WLGITGSVNRD 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	12/51 (24%)
		AMN1	<226..>334	CDD:187754	47/189 (25%)
		leucine-rich repeat	236..256	CDD:275381	10/70 (14%)
		leucine-rich repeat	263..288	CDD:275381	9/25 (36%)
		leucine-rich repeat	289..314	CDD:275381	6/32 (19%)
		leucine-rich repeat	315..347	CDD:275381	19/84 (23%)
		AMN1	347..524	CDD:187754	60/191 (31%)
		leucine-rich repeat	348..373	CDD:275381	8/24 (33%)
		leucine-rich repeat	374..398	CDD:275381	5/23 (22%)
		leucine-rich repeat	399..424	CDD:275381	12/25 (48%)
		leucine-rich repeat	425..450	CDD:275381	6/24 (25%)
		leucine-rich repeat	451..475	CDD:275381	9/24 (38%)
		leucine-rich repeat	476..501	CDD:275381	8/32 (25%)
AT2G17020	NP_565400.1	F-box	22..60	CDD:279040	11/37 (30%)
		leucine-rich repeat	53..87	CDD:275381	2/33 (6%)
		leucine-rich repeat	89..111	CDD:275381	6/21 (29%)
		leucine-rich repeat	112..137	CDD:275381	2/24 (8%)
		leucine-rich repeat	138..168	CDD:275381	9/30 (30%)
		leucine-rich repeat	169..215	CDD:275381	5/45 (11%)
		leucine-rich repeat	236..260	CDD:275381	9/25 (36%)
		AMN1	<246..394	CDD:187754	36/148 (24%)
		leucine-rich repeat	261..292	CDD:275381	6/31 (19%)
		leucine-rich repeat	294..315	CDD:275381	8/20 (40%)
		leucine-rich repeat	328..353	CDD:275381	5/24 (21%)
		AMN1	337..497	CDD:187754	42/161 (26%)
		leucine-rich repeat	354..379	CDD:275381	0/24 (0%)
		leucine-rich repeat	380..404	CDD:275381	8/24 (33%)
		leucine-rich repeat	405..429	CDD:275381	5/23 (22%)
		leucine-rich repeat	430..455	CDD:275381	12/25 (48%)
		leucine-rich repeat	456..481	CDD:275381	6/24 (25%)
		leucine-rich repeat	482..509	CDD:275381	9/26 (35%)
		leucine-rich repeat	510..529	CDD:275381	4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820