Protein Alignment Ppa and fbxl17

DIOPT Version :10

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_073766094.1
• Gene: fbxl17 / 795023
• ZFINID: ZDB-GENE-111013-3
• Length: 600
• Species: Danio rerio
• Alignment Length: 477
• Identity: 116/477 - (24%)
• Similarity: 218/477 - (45%)
• Gaps: 69/477 - (14%)

  Fly    90 PPHHQLQTLPPALYLQHAAAAAAAAAAAAAHAQHHHHHHHHLP-------------HRPASPE-- 139
            |..|.|  ||....|..::::::::|:....|....|..   |             ...||.|
Zfish   152 PDSHCL--LPSICPLPSSSSSSSSSASEEDGATAGRHSD---PGGATTCSSSSCCCQTEASEEIK 211

  Fly   140 SPPPVEGTHISNLFPELLEQIFEHLPVRDLGRAAQ-VCTAWRDAAYAKSVWKGVEAKLHLKRSSP 203
            |....:.:||:.|...:|.::|.||.|::...||. ||..|||.......||.::..
Zfish   212 STENTDTSHINQLPSSILLKVFSHLSVKERCLAASLVCKYWRDLCLDFQFWKQIDLS-------- 268

  Fly   204 SLFNCLVKRGIKKVQILSLRRSLKDLVLGVPA----LTSLNLSGCFNVADMNLGHAFSVDLPNLK 264
                     |:::|:        .||::.:.:    :|.:|:|.|.||.|..: .|.:.:...|.
Zfish   269 ---------GLQQVK--------DDLLVKIASRRQNVTEINISDCRNVQDHGV-CALASNCAGLI 315

  Fly   265 TLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQ 329
            ......|||::|.||..:|.|...|:.:.:|....:|:..|.|:....|:||.::...|:.|||:
Zfish   316 KYTAYRCKQLSDVSLSTVAIHCPLLQKVHVGNQDKLTDHALKLLGDHCKELKDVHFGQCYSISDE 380

  Fly   330 GIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLA 394
            |:..|       |:|..:|:.:.:|:.:.::|.::...|:....|:.:....| |||..|:.||.
Zfish   381 GLMSL-------AQGCNKLQRIYMQENKLVTDRSVQAFAEHCPDLQFVGFMGC-SVTSQGVIHLT 437

  Fly   395 RMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQC 459
            |:..|..|:||....:::..:..:......:.||::.....|:|:.:..||:....|:.|.|..|
Zfish   438 RLQHLSSLDLRHISELNNETVMEVVRKCRNLTSLNLCLNWTINDRCVEIIAKEGRSLKELYLVSC 502

  Fly   460 QITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGID-IIMK 523
            :||||.::.|.:....:|.::.|.|..|||:|...:|:...:|:.:.|..|.:::.:.:: ::::
Zfish   503 KITDHALIAIGQYSSTIETVDAGWCKEITDQGATQIAKSSKSLRYLGLMRCDKVNEETVERLVLQ 567

  Fly   524 LPKLQKLNLGLWLVRXCVHHDC 545
            .|.         :|. .|..||
Zfish   568 YPH---------IVFSTVMQDC 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box_FBXL14	150..190	CDD:438897	13/40 (33%)
		AMN1	<226..>334	CDD:187754	32/111 (29%)
		leucine-rich repeat	236..256	CDD:275381	7/19 (37%)
		leucine-rich repeat	263..288	CDD:275381	9/24 (38%)
		leucine-rich repeat	289..314	CDD:275381	5/24 (21%)
		leucine-rich repeat	315..347	CDD:275381	10/31 (32%)
		AMN1	347..524	CDD:187754	43/177 (24%)
		leucine-rich repeat	348..373	CDD:275381	4/24 (17%)
		leucine-rich repeat	374..398	CDD:275381	9/23 (39%)
		leucine-rich repeat	399..424	CDD:275381	4/24 (17%)
		leucine-rich repeat	425..450	CDD:275381	6/24 (25%)
		leucine-rich repeat	451..475	CDD:275381	9/23 (39%)
		leucine-rich repeat	476..501	CDD:275381	8/24 (33%)
fbxl17	XP_073766094.1	None