DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and FBXL15

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:XP_005270206.1 Gene:FBXL15 / 79176 HGNCID:28155 Length:387 Species:Homo sapiens


Alignment Length:275 Identity:75/275 - (27%)
Similarity:127/275 - (46%) Gaps:54/275 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   279 LGRIAQHLRNLETLELGGC---------CNITNTGLLLIAWGLKKLKHLNLRSC--WHISDQGIG 332
            |.|:::..|:|..|.|.|.         ..|....|..:....:.|:.|.|..|  | :||:.: 
Human   131 LQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEW-LSDEDL- 193

  Fly   333 HLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLA-RM 396
             :...:|     |.||..:.|..|.:||..|||.:|:|...|:.::|:.|..|....|:.|| |.
Human   194 -VPVLAR-----NPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRC 252

  Fly   397 PKLEQLNLRSCDNISDIGMAYLTE-GGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQ 460
            |.||:|:|.:|..:.|..:.||.: .|:|:.||                        ||::| ..
Human   253 PALEELDLTACRQLKDEAIVYLAQRRGAGLRSL------------------------SLAVN-AN 292

  Fly   461 ITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGC--------TQLSSKG 517
            :.|..:.::|:...||.:|::..|.|:...|::||||....|:::.:..|        ::|..:|
Human   293 VGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKRG 357

  Fly   518 IDIIMKLPKLQKLNL 532
            :||.::.|..|.|.|
Human   358 VDIDVEPPLHQALVL 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689
AMN1 <226..>334 CDD:187754 16/65 (25%)
leucine-rich repeat 236..256 CDD:275381
leucine-rich repeat 263..288 CDD:275381 2/8 (25%)
leucine-rich repeat 289..314 CDD:275381 6/33 (18%)
leucine-rich repeat 315..347 CDD:275381 9/33 (27%)
AMN1 347..524 CDD:187754 53/186 (28%)
leucine-rich repeat 348..373 CDD:275381 10/24 (42%)
leucine-rich repeat 374..398 CDD:275381 8/24 (33%)
leucine-rich repeat 399..424 CDD:275381 9/25 (36%)
leucine-rich repeat 425..450 CDD:275381 2/24 (8%)
leucine-rich repeat 451..475 CDD:275381 5/23 (22%)
leucine-rich repeat 476..501 CDD:275381 9/24 (38%)
FBXL15XP_005270206.1 F-box 105..>142 CDD:279040 3/10 (30%)
leucine-rich repeat 149..175 CDD:275381 2/25 (8%)
leucine-rich repeat 176..202 CDD:275381 9/33 (27%)
leucine-rich repeat 203..228 CDD:275381 10/24 (42%)
AMN1 <226..>353 CDD:187754 38/151 (25%)
leucine-rich repeat 229..254 CDD:275381 8/24 (33%)
leucine-rich repeat 255..281 CDD:275381 9/25 (36%)
leucine-rich repeat 282..307 CDD:275381 7/49 (14%)
leucine-rich repeat 308..332 CDD:275381 9/23 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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