DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and Fbxl22

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_780415.1 Gene:Fbxl22 / 74165 MGIID:1921415 Length:236 Species:Mus musculus


Alignment Length:208 Identity:62/208 - (29%)
Similarity:92/208 - (44%) Gaps:27/208 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   148 HISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVW------KGVEAKLHLKRSSPSLF 206
            ||:.|..|.|..:|..|........::.|:..||.....::|      ...|.|....|.||:|.
Mouse     2 HITQLNRECLLCLFSFLDKDSRRSLSRTCSQLRDVFEDPTLWPLLHFHSLAELKKDNFRLSPALR 66

  Fly   207 NCLVKRGIKKVQILS--------LRRSL--------KDLVLGV----PALTSLNLSGCFNVADMN 251
            :..:.....:||:.|        |:||:        .|.:|.|    |.|||:.||||.:|.|..
Mouse    67 SLSICWHSSRVQVCSIEDWLKSALQRSICSQHESLVNDFLLQVCNRCPNLTSVTLSGCGHVTDDC 131

  Fly   252 LGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLK 316
            |.... :..|.|:||.|..|.::|:.:|..:|.|.|.|:||.:..|.|::..|||.:......|:
Mouse   132 LARLL-LSCPRLRTLRLENCARVTNRTLAAVAAHGRALQTLHVDFCRNVSAAGLLRLRAACPNLR 195

  Fly   317 HLNLRSCWHISDQ 329
            ....||...|.||
Mouse   196 LSAERSAAMIPDQ 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 10/46 (22%)
AMN1 <226..>334 CDD:187754 39/116 (34%)
leucine-rich repeat 236..256 CDD:275381 10/19 (53%)
leucine-rich repeat 263..288 CDD:275381 9/24 (38%)
leucine-rich repeat 289..314 CDD:275381 8/24 (33%)
leucine-rich repeat 315..347 CDD:275381 6/15 (40%)
AMN1 347..524 CDD:187754
leucine-rich repeat 348..373 CDD:275381
leucine-rich repeat 374..398 CDD:275381
leucine-rich repeat 399..424 CDD:275381
leucine-rich repeat 425..450 CDD:275381
leucine-rich repeat 451..475 CDD:275381
leucine-rich repeat 476..501 CDD:275381
Fbxl22NP_780415.1 F-box-like 3..43 CDD:403981 9/39 (23%)
LRR 1 15..40 5/24 (21%)
LRR 2 43..72 7/28 (25%)
AMN1 45..>200 CDD:187754 46/155 (30%)
LRR 3 98..123 8/24 (33%)
leucine-rich repeat 116..141 CDD:275381 10/25 (40%)
LRR 4 124..149 9/25 (36%)
leucine-rich repeat 142..167 CDD:275381 9/24 (38%)
LRR 5 150..175 9/24 (38%)
leucine-rich repeat 168..193 CDD:275381 8/24 (33%)
LRR 6 176..201 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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