Protein Alignment Ppa and Fbxl15

DIOPT Version :10

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001365702.1
• Gene: Fbxl15 / 68431
• MGIID: 1915681
• Length: 336
• Species: Mus musculus
• Alignment Length: 404
• Identity: 95/404 - (23%)
• Similarity: 155/404 - (38%)
• Gaps: 137/404 - (33%)

  Fly   156 LLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGIKKVQIL 220
            ||..:...:|:|.|.|..:|..|:|           ...:|||.|
Mouse    28 LLPHVLNWVPLRQLLRLQRVSRAFR-----------ALVQLHLAR-------------------- 61

  Fly   221 SLRRSLKDLVLGVPALTSLNLSGCFNVADMNLG------HAFSVDLPNLKTLDLSLC-------- 271
             |||                    |:.|.::.|      || ...:|....|..|.|
Mouse    62 -LRR--------------------FDAAQVSRGPEPRPRHA-PAWVPPSPRLQASPCCAVNPSRP 104

  Fly   272 ---KQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGH 333
               .||...:|.|:.:....|:.|.|..|..                        | :||:.:
Mouse   105 RVGPQIPRAALARLLRDAEGLQELALAPCHE------------------------W-LSDEDL-- 142

  Fly   334 LAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLA-RMP 397
            :...:|     |.||..:.|..|.:||..|||.:|:|...|:.::|:.|..|....|:.|| |.|
Mouse   143 VPVLAR-----NPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCP 202

  Fly   398 KLEQLNLRSCDNISDIGMAYLTE-GGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQI 461
            .||:|:|.:|..:.|..:.||.: .|:|:.||                        ||::| ..:
Mouse   203 ALEELDLTACRQLKDEAIVYLAQRRGAGLRSL------------------------SLAVN-ANV 242

  Fly   462 TDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGC--------TQLSSKGI 518
            .|..:.::|:...:||:|::..|.|:...|::||||....|:::.:..|        ::|..:|:
Mouse   243 GDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGV 307

  Fly   519 DIIMKLPKLQKLNL 532
            ||.::.|..|.|.|
Mouse   308 DIDVEPPLHQALVL 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box_FBXL14	150..190	CDD:438897	9/33 (27%)
		AMN1	<226..>334	CDD:187754	20/124 (16%)
		leucine-rich repeat	236..256	CDD:275381	4/25 (16%)
		leucine-rich repeat	263..288	CDD:275381	7/35 (20%)
		leucine-rich repeat	289..314	CDD:275381	4/24 (17%)
		leucine-rich repeat	315..347	CDD:275381	5/31 (16%)
		AMN1	347..524	CDD:187754	53/186 (28%)
		leucine-rich repeat	348..373	CDD:275381	10/24 (42%)
		leucine-rich repeat	374..398	CDD:275381	8/24 (33%)
		leucine-rich repeat	399..424	CDD:275381	9/25 (36%)
		leucine-rich repeat	425..450	CDD:275381	2/24 (8%)
		leucine-rich repeat	451..475	CDD:275381	5/23 (22%)
		leucine-rich repeat	476..501	CDD:275381	10/24 (42%)
Fbxl15	NP_001365702.1	F-box_FBXL15	19..62	CDD:438898	13/65 (20%)
		FBXL3_LRR-like	<107..182	CDD:480268	25/106 (24%)
		leucine-rich repeat	125..151	CDD:275381	9/57 (16%)
		leucine-rich repeat	152..177	CDD:275381	10/24 (42%)
		AMN1	<175..>304	CDD:187754	39/153 (25%)
		leucine-rich repeat	178..203	CDD:275381	8/24 (33%)
		leucine-rich repeat	204..230	CDD:275381	9/25 (36%)
		leucine-rich repeat	231..256	CDD:275381	7/49 (14%)
		leucine-rich repeat	257..281	CDD:275381	10/23 (43%)