DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppa and Fbxl20

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	XP_017453008.1	Gene:	Fbxl20 / 64039	RGDID:	621722	Length:	453	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	122/393 - (31%)
Similarity:	187/393 - (47%)	Gaps:	55/393 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 ELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGI--KKV 217
            |||.:||..|.|..|.|.|||..||...|...|.|:.::           ||:  .:|.|  :.|
  Rat    48 ELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRID-----------LFD--FQRDIEGRVV 99

  Fly   218 QILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQITD---TSL 279
            :.:|.|..        ..|..|:|.||..|.| |....|:.:..|::.|.|:.|.:.||   |||
  Rat   100 ENISKRCG--------GFLRKLSLRGCLGVGD-NALRTFAQNCRNIEVLSLNGCTKTTDATCTSL 155

  Fly   280 GRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHL----AGFSRE 340
            .:....||:   |:|..|.:|||..|..::.|...|:.||:..|..::..||..|    .|....
  Rat   156 SKFCSKLRH---LDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKAL 217

  Fly   341 TAEGNLQLE-----YLG----------LQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGL 390
            ..:|..|||     |:|          ||.|.:::||.|..|.:|...|:|:..|.|.::||:.|
  Rat   218 FLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAIL 282

  Fly   391 KHLAR-MPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSL 454
            ..|.: .|:|..|.:..|..::|:|...|......:..:|:..|.:|:|..|..::....||:.|
  Rat   283 NALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVL 347

  Fly   455 SLNQCQ-ITDHGMLKI---AKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSS 515
            ||:.|: |||.|:..:   |.|..:||.:.:..|..|||..|:.| :...:|:.|:||.|.|::.
  Rat   348 SLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHL-KSCHSLERIELYDCQQITR 411

  Fly   516 KGI 518
            .||
  Rat   412 AGI 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	16/34 (47%)
		AMN1	<226..>334	CDD:187754	34/110 (31%)
		leucine-rich repeat	236..256	CDD:275381	8/19 (42%)
		leucine-rich repeat	263..288	CDD:275381	9/27 (33%)
		leucine-rich repeat	289..314	CDD:275381	8/24 (33%)
		leucine-rich repeat	315..347	CDD:275381	9/35 (26%)
		AMN1	347..524	CDD:187754	61/192 (32%)
		leucine-rich repeat	348..373	CDD:275381	12/39 (31%)
		leucine-rich repeat	374..398	CDD:275381	8/24 (33%)
		leucine-rich repeat	399..424	CDD:275381	6/24 (25%)
		leucine-rich repeat	425..450	CDD:275381	5/24 (21%)
		leucine-rich repeat	451..475	CDD:275381	11/27 (41%)
		leucine-rich repeat	476..501	CDD:275381	8/24 (33%)
Fbxl20	XP_017453008.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910