DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and Fbxo39

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:XP_006533964.2 Gene:Fbxo39 / 628100 MGIID:3505735 Length:480 Species:Mus musculus


Alignment Length:386 Identity:83/386 - (21%)
Similarity:139/386 - (36%) Gaps:125/386 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   132 PHRPASPESPPPVEGTHISNL--------FPEL-LEQIFEHLPVRDLGRAAQVCTAWRDAAYAKS 187
            ||..|..:.|...|...::.|        .|:: |.::|..|..||..|||.||..|....|:..
Mouse    27 PHHYAVHQGPLMDEDCEVTQLQEQSCWATLPDVCLRRVFWWLGDRDRSRAALVCRKWNQIMYSAD 91

  Fly   188 VWK-------GVEAKLHLKRSSPSLFNCLVKRGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCF 245
            :|:       |..:::|......:|:.      |||     ..|.|:.|        .:.....:
Mouse    92 LWRYRTITFSGRPSRVHASEFESALWY------IKK-----FGRYLEHL--------EIKFLNPY 137

  Fly   246 NVADMNLGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAW 310
            |..   |...|.|.:..|.:     |       ||:....||:|                     
Mouse   138 NAV---LTKKFQVTMRGLLS-----C-------LGKSNNRLRSL--------------------- 166

  Fly   311 GLKKLKHLNL-RSCWHISDQG--IGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLT 372
               .::||.| |..|..|.:|  |..|:.|.::..:   .|::|.|:.. ||:.|...||...|:
Mouse   167 ---SIQHLELDRLVWRNSIRGSLIKSLSFFLKKMGK---HLDHLSLKGA-RLTVEQGCHILNSLS 224

  Fly   373 SLKSINLSFCVSVTDSGLKHLARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSF----- 432
            .:::.|::..:::.|....|||                        ..|.|..|....:|     
Mouse   225 YMQNENMASELNIEDFFSHHLA------------------------VYGSSQFNKAMATFRNLTF 265

  Fly   433 ------CDKISDQALTHIAQ-GLYRLRSLSLNQCQITD-HGM----LKIAKALHELENLNI 481
                  |  |||:.|..::: ....||:::: :|.:.| ||.    :..||...:..||.:
Mouse   266 LTLNYNC--ISDELLETLSENNAGTLRTMNI-KCHVHDPHGQVVWGMSWAKLARQASNLKV 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 14/49 (29%)
AMN1 <226..>334 CDD:187754 21/110 (19%)
leucine-rich repeat 236..256 CDD:275381 2/19 (11%)
leucine-rich repeat 263..288 CDD:275381 5/24 (21%)
leucine-rich repeat 289..314 CDD:275381 1/24 (4%)
leucine-rich repeat 315..347 CDD:275381 10/34 (29%)
AMN1 347..524 CDD:187754 33/152 (22%)
leucine-rich repeat 348..373 CDD:275381 9/24 (38%)
leucine-rich repeat 374..398 CDD:275381 5/23 (22%)
leucine-rich repeat 399..424 CDD:275381 1/24 (4%)
leucine-rich repeat 425..450 CDD:275381 7/36 (19%)
leucine-rich repeat 451..475 CDD:275381 8/28 (29%)
leucine-rich repeat 476..501 CDD:275381 2/6 (33%)
Fbxo39XP_006533964.2 F-box-like 53..94 CDD:372399 13/40 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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