Protein Alignment Ppa and skp2

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_005161246.1
• Gene: skp2 / 563708
• ZFINID: ZDB-GENE-030219-158
• Length: 427
• Species: Danio rerio
• Alignment Length: 414
• Identity: 94/414 - (22%)
• Similarity: 146/414 - (35%)
• Gaps: 170/414 - (41%)

  Fly   155 ELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVE----AKLHLKRSSPSLFNCLVKRGIK 215
            |||..||..|.::||.|.::||..|...|:.:|:|..|:    |:|..:..
Zfish   111 ELLLGIFSRLSLQDLLRTSRVCKRWHRLAFDESLWHSVDLVGKAQLDAELG-------------- 161

  Fly   216 KVQILS---LRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKT--LDLSLC---K 272
              |:||   ||.......:|.|:..|                     .|:|:.  ||.|.|   .
Zfish   162 --QVLSAGVLRLRCPHTCIGQPSFKS---------------------TPSLRVQHLDFSNCTVET 203

  Fly   273 QITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHLAGF 337
            .:.:..|.| .:||:|| :||          ||:|                   ||..|..||
Zfish   204 SVLEDVLSR-CKHLQNL-SLE----------GLVL-------------------SDNIIYSLA-- 235

  Fly   338 SRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHL----ARMP- 397
                  .|.::..|.|..|...|.|:|..:....|.::.:|:|:|    |....|:    :.:|
Zfish   236 ------QNPEIIRLNLCGCSGFSPESLTEMLTACTRIEEMNVSWC----DFSNLHIQAIASNIPS 290

  Fly   398 KLEQLNL----------------RSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALT---- 442
            .:.|||:                :.|.||:|:                     .:||..|.
Zfish   291 SVSQLNISGYRQNLTMEDVKAIVKRCPNITDL---------------------DLSDSVLVTTDS 334

  Fly   443 -HIAQGLYRLRSLSLNQC-QITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTI 505
             .:.|.|..||.|.|::| ||....::...|.|                           ||:|:
Zfish   335 FPVLQQLSSLRHLGLSRCYQIHPASLIDFEKFL---------------------------NLQTL 372

  Fly   506 DLYGCTQLSSKGIDIIMK-LPKLQ 528
            :::|..|.|.  :.|:.| ||.:|
Zfish   373 EVFGLIQDSY--LPILCKSLPHIQ 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	14/34 (41%)
		AMN1	<226..>334	CDD:187754	23/112 (21%)
		leucine-rich repeat	236..256	CDD:275381	1/19 (5%)
		leucine-rich repeat	263..288	CDD:275381	9/29 (31%)
		leucine-rich repeat	289..314	CDD:275381	6/24 (25%)
		leucine-rich repeat	315..347	CDD:275381	6/31 (19%)
		AMN1	347..524	CDD:187754	42/204 (21%)
		leucine-rich repeat	348..373	CDD:275381	6/24 (25%)
		leucine-rich repeat	374..398	CDD:275381	6/28 (21%)
		leucine-rich repeat	399..424	CDD:275381	7/40 (18%)
		leucine-rich repeat	425..450	CDD:275381	5/29 (17%)
		leucine-rich repeat	451..475	CDD:275381	9/24 (38%)
		leucine-rich repeat	476..501	CDD:275381	0/24 (0%)
skp2	XP_005161246.1	F-box-like	105..150	CDD:289689	16/38 (42%)
		leucine-rich repeat	168..190	CDD:275381	6/42 (14%)
		AMN1	190..341	CDD:187754	45/214 (21%)
		leucine-rich repeat	191..215	CDD:275381	6/24 (25%)
		leucine-rich repeat	216..239	CDD:275381	14/60 (23%)
		leucine-rich repeat	240..265	CDD:275381	6/24 (25%)
		leucine-rich repeat	266..291	CDD:275381	6/28 (21%)
		leucine-rich repeat	292..318	CDD:275381	4/25 (16%)
		leucine-rich repeat	319..343	CDD:275381	7/44 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910