Protein Alignment Ppa and Skp2

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 397
• Identity: 87/397 - (21%)
• Similarity: 159/397 - (40%)
• Gaps: 104/397 - (26%)

  Fly   143 PVEGTHISN-------LFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKR 200
            |....||::       |..|:|..||:.||.:.|.|.|.||..:...:..:::|..::  |.|:.
  Fly   226 PAMSAHINSGINYFERLSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLD--LGLRT 288

  Fly   201 SSPSLFNCLVKRGIKKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKT 265
            ..|.....:|:||:..:::  .:.|:::     ||.....                .|....|:.
  Fly   289 IRPGALEQIVRRGVLVIRL--AQTSIQE-----PAFAPYT----------------EVFRTRLQY 330

  Fly   266 LDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQG 330
            ||||:. .||.:||..:..|.|.                       |||:...|:    .:.|..
  Fly   331 LDLSMA-SITRSSLLTLLSHCRQ-----------------------LKKISLENI----ELDDDI 367

  Fly   331 IGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSG---LKH 392
            ...:|        .|..||.:.|.....|:..::..:.:.||||.|:|:|:.....|:.   :.|
  Fly   368 CAEIA--------KNEALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTALVTH 424

  Fly   393 LARMPKLEQLNLRSCDNI-SDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSL 456
            ::  |.|.:||:..|..: .|..:|.|.:....:..||:|.|:.::...:|.|.: ...|..||:
  Fly   425 IS--PNLIRLNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMK-FKMLEYLSV 486

  Fly   457 NQCQITDHGMLKIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDII 521
            ::|.:..      |....||::                    :.:|..:|::|  .||...::::
  Fly   487 SRCYLIP------ATKFIELKS--------------------MPSLTYLDIFG--MLSDTAMEVL 523

  Fly   522 MK-LPKL 527
            .| |||:
  Fly   524 EKQLPKM 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	13/47 (28%)
		AMN1	<226..>334	CDD:187754	19/107 (18%)
		leucine-rich repeat	236..256	CDD:275381	0/19 (0%)
		leucine-rich repeat	263..288	CDD:275381	10/24 (42%)
		leucine-rich repeat	289..314	CDD:275381	1/24 (4%)
		leucine-rich repeat	315..347	CDD:275381	4/31 (13%)
		AMN1	347..524	CDD:187754	40/181 (22%)
		leucine-rich repeat	348..373	CDD:275381	5/24 (21%)
		leucine-rich repeat	374..398	CDD:275381	6/26 (23%)
		leucine-rich repeat	399..424	CDD:275381	7/25 (28%)
		leucine-rich repeat	425..450	CDD:275381	6/24 (25%)
		leucine-rich repeat	451..475	CDD:275381	5/23 (22%)
		leucine-rich repeat	476..501	CDD:275381	1/24 (4%)
Skp2	NP_730815.2	F-box-like	239..284	CDD:289689	13/46 (28%)
		leucine-rich repeat	302..327	CDD:275381	4/47 (9%)
		AMN1	309..480	CDD:187754	49/230 (21%)
		leucine-rich repeat	328..352	CDD:275381	10/24 (42%)
		leucine-rich repeat	353..376	CDD:275381	7/34 (21%)
		leucine-rich repeat	377..402	CDD:275381	5/24 (21%)
		leucine-rich repeat	403..428	CDD:275381	6/26 (23%)
		leucine-rich repeat	429..455	CDD:275381	7/25 (28%)
		leucine-rich repeat	456..480	CDD:275381	6/24 (25%)
		leucine-rich repeat	481..500	CDD:275381	5/24 (21%)
		leucine-rich repeat	506..529	CDD:275381	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457939
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840