DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and Fbxl22

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001102239.1	Gene:	Fbxl22 / 363083	RGDID:	1311830	Length:	236	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	52/185 - (28%)
Similarity:	81/185 - (43%)	Gaps:	27/185 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 HISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGV------EAKLHLKRSSPSLF 206
            ||:.|..|.|.::|..|........::.|:..||.....::|..:      |.|....|.||:|.
  Rat     2 HITQLNRECLLRLFSFLDKDSRKSLSRTCSQLRDVFEDPTLWSLLHFHSLTELKKDNFRLSPALR 66

  Fly   207 NCLVKRGIKKVQILSLRRSLK----------------DLVLGV----PALTSLNLSGCFNVADMN 251
            :..:.....:||:.|:...||                |.:|.|    |.|.|:.||||.:|.|..
  Rat    67 SLSICWHSSRVQVCSIEDWLKSAFQRSICSQHENLVNDFLLQVCNRCPNLASVTLSGCGHVTDDC 131

  Fly   252 LGHAFSVDLPNLKTLDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLL 306
            |.... :..|.|:.|.|..|.::|:.:|..:|.|.|.|:|..:..|.|::..|||
  Rat   132 LARLL-LGCPRLRALRLENCARVTNRTLAAVAAHGRALQTFHVDFCRNVSAAGLL 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	9/40 (23%)
		AMN1	<226..>334	CDD:187754	32/101 (32%)
		leucine-rich repeat	236..256	CDD:275381	9/19 (47%)
		leucine-rich repeat	263..288	CDD:275381	8/24 (33%)
		leucine-rich repeat	289..314	CDD:275381	7/18 (39%)
		leucine-rich repeat	315..347	CDD:275381
		AMN1	347..524	CDD:187754
		leucine-rich repeat	348..373	CDD:275381
		leucine-rich repeat	374..398	CDD:275381
		leucine-rich repeat	399..424	CDD:275381
		leucine-rich repeat	425..450	CDD:275381
		leucine-rich repeat	451..475	CDD:275381
		leucine-rich repeat	476..501	CDD:275381
Fbxl22	NP_001102239.1	F-box-like	3..43	CDD:403981	9/39 (23%)
		AMN1	44..>191	CDD:187754	41/143 (29%)
		leucine-rich repeat	116..141	CDD:275381	9/25 (36%)
		leucine-rich repeat	142..167	CDD:275381	8/24 (33%)
		leucine-rich repeat	168..193	CDD:275381	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810