DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and Fbxl6

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_001005563.1 Gene:Fbxl6 / 362941 RGDID:1359687 Length:535 Species:Rattus norvegicus


Alignment Length:506 Identity:136/506 - (26%)
Similarity:190/506 - (37%) Gaps:126/506 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 HHLLRFTPYALHHRPPHHQLQTLPPALYLQHAAAAAAAAAAAAAHAQHHHHHHHHLPHRPASPES 140
            :|||:.....|       .|..|.|.....|..|...|..:.|..           |...|.|.:
  Rat    41 YHLLQADSMLL-------VLPDLEPTRARAHRRAPRRAPRSLARG-----------PTAVAKPRA 87

  Fly   141 PPPVEGTHISNL-------FP-ELLEQIF-----EHLPVRDLGRAAQVCTAWRDAAYAKSVWK-- 190
            .|..|.:....|       .| |:|..||     .|.|:..|||||:||..|.:|....|:|.  
  Rat    88 KPRPEPSLDQGLDSGWGDRIPLEVLVHIFGLLVAAHGPMPFLGRAARVCRHWHEATSHPSLWHTV 152

  Fly   191 -------GVEAKLHLKRSSPSLFNC---LVKRGIKKVQILSL------RRSLKDLVLG-VPALTS 238
                   |..||.:|| ....|..|   |:.....::|.|:|      ..|:.:||.. .|.||.
  Rat   153 TLSPALVGRAAKGNLK-GEKKLLACLEWLIPNRFSQLQRLTLIHWKSQVHSVLELVSKFCPRLTF 216

  Fly   239 LNLSGCFNVADMNL-------GHAFSVDL------------------PNLKTLDLSLCKQIT--- 275
            |.||.|..|....|       ....|:||                  ..::.|.|:...|.|   
  Rat   217 LKLSDCHGVTAETLVMLAKACCQLHSLDLHHSMVESTAVVSFLEEAGSRMRRLWLTYSSQTTAIL 281

  Fly   276 DTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKK-------LKHLNL----RSCWHISDQ 329
            ...||.....|:.|| :..|..||  ||.|.|....|::       |:.|||    :.|...:.|
  Rat   282 GALLGNCCSQLQVLE-VSAGMSCN--NTPLQLPVEALQRGCPQLQVLRLLNLIWLPKPCGRGAPQ 343

  Fly   330 GIGHLAGFSRETAEGNLQLEYLGL--QDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKH 392
            |    .||.        .||.|.|  ..|..:|:|.||.:......|:.::|..|..:|.:||.|
  Rat   344 G----PGFP--------SLEELCLAGSTCSFVSNEVLGRLLHCSPKLRLLDLRGCARITPTGLCH 396

  Fly   393 LARMPKLEQLNLRSCDNISDIGMAYLTEGG--------SGINSLDVS---FCDKISDQAL---TH 443
            |. ..:||||.| ....:|| |:|...:|.        ..:..||.|   |.:|..:|||   :.
  Rat   397 LP-CQELEQLYL-GLYGMSD-GLALAKDGSPLLTQKWYHTLRELDFSGQGFSEKDLEQALAVFSG 458

  Fly   444 IAQGL-YRLRSLSLNQCQITDHGMLKIAKALHELENLNIGQCSRITDKGLQ 493
            ..:|| ..|.||:|...::|...:..:..:...|..||:..| |...:||:
  Rat   459 TTEGLPPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESC-RCLPRGLK 508

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 18/53 (34%)
AMN1 <226..>334 CDD:187754 38/147 (26%)
leucine-rich repeat 236..256 CDD:275381 8/26 (31%)
leucine-rich repeat 263..288 CDD:275381 7/27 (26%)
leucine-rich repeat 289..314 CDD:275381 10/24 (42%)
leucine-rich repeat 315..347 CDD:275381 9/35 (26%)
AMN1 347..524 CDD:187754 49/164 (30%)
leucine-rich repeat 348..373 CDD:275381 9/26 (35%)
leucine-rich repeat 374..398 CDD:275381 8/23 (35%)
leucine-rich repeat 399..424 CDD:275381 10/32 (31%)
leucine-rich repeat 425..450 CDD:275381 10/31 (32%)
leucine-rich repeat 451..475 CDD:275381 5/23 (22%)
leucine-rich repeat 476..501 CDD:275381 7/18 (39%)
Fbxl6NP_001005563.1 F-box-like 105..155 CDD:289689 18/49 (37%)
AMN1 171..390 CDD:187754 59/233 (25%)
leucine-rich repeat 188..213 CDD:275381 6/24 (25%)
leucine-rich repeat 214..239 CDD:275381 8/24 (33%)
leucine-rich repeat 240..291 CDD:275381 9/50 (18%)
leucine-rich repeat 292..321 CDD:275381 11/31 (35%)
leucine-rich repeat 322..349 CDD:275381 9/38 (24%)
AMN1 <349..500 CDD:187754 45/153 (29%)
leucine-rich repeat 350..377 CDD:275381 9/26 (35%)
leucine-rich repeat 378..401 CDD:275381 8/23 (35%)
leucine-rich repeat 434..466 CDD:275381 10/31 (32%)
leucine-rich repeat 467..491 CDD:275381 5/23 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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