DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and Kdm2a

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:XP_038939767.1 Gene:Kdm2a / 361700 RGDID:1309419 Length:1166 Species:Rattus norvegicus


Alignment Length:310 Identity:79/310 - (25%)
Similarity:121/310 - (39%) Gaps:71/310 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   155 ELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSS---PSLFNCLVKRGIKK 216
            |:...:|.:|..|:|....:||..|......|.:|    .|:.|.|..   |...:.::||    
  Rat   900 EVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLW----TKIDLSRCKAIVPQALSGIIKR---- 956

  Fly   217 VQILSL--------RRSLKDLVLGVPALTSLNLSGCFNVADMNLGHAFSVDLPNLKTLDLSLCKQ 273
             |.:||        ::.|..||..:|.|..|.|:||...|...|.   :...|.|:||||.....
  Rat   957 -QPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALS---TSSCPLLRTLDLRWAVG 1017

  Fly   274 ITDTSLGRI------------AQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHI 326
            |.|..:..:            ...|||:....|.| .:||:..|.||...:..|..|:|..|.|:
  Rat  1018 IKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAG-LDITDATLRLIIRHMPLLSRLDLSHCSHL 1081

  Fly   327 SDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLK 391
            :||....|......|   ...|..|.:..|.:|:|:.|..:.: :.::..|:|..|..:|....:
  Rat  1082 TDQSSNLLTAVGSST---RYSLTELNMAGCNKLTDQTLFFLRR-IANVTLIDLRGCKQITRKACE 1142

  Fly   392 HLARMPKLEQLNLRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQAL 441
            |.                |||:          .||||   :|  :||:.|
  Rat  1143 HF----------------ISDL----------SINSL---YC--LSDEKL 1161

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 9/34 (26%)
AMN1 <226..>334 CDD:187754 36/119 (30%)
leucine-rich repeat 236..256 CDD:275381 7/19 (37%)
leucine-rich repeat 263..288 CDD:275381 8/36 (22%)
leucine-rich repeat 289..314 CDD:275381 7/24 (29%)
leucine-rich repeat 315..347 CDD:275381 9/31 (29%)
AMN1 347..524 CDD:187754 22/95 (23%)
leucine-rich repeat 348..373 CDD:275381 6/24 (25%)
leucine-rich repeat 374..398 CDD:275381 5/23 (22%)
leucine-rich repeat 399..424 CDD:275381 3/24 (13%)
leucine-rich repeat 425..450 CDD:275381 8/17 (47%)
leucine-rich repeat 451..475 CDD:275381
leucine-rich repeat 476..501 CDD:275381
Kdm2aXP_038939767.1 cupin_RmlC-like 204..304 CDD:424065
JHD 309..>344 CDD:407680
CTD_KDM2A 455..522 CDD:412025
zf-CXXC <581..614 CDD:366873
PHD_KDM2A 624..680 CDD:277113
F-box-like 900..938 CDD:403981 11/41 (27%)
leucine-rich repeat 934..958 CDD:275381 7/32 (22%)
AMN1 936..1142 CDD:187754 57/218 (26%)
leucine-rich repeat 959..982 CDD:275381 5/22 (23%)
leucine-rich repeat 983..1006 CDD:275381 7/25 (28%)
leucine-rich repeat 1007..1044 CDD:275381 8/36 (22%)
leucine-rich repeat 1045..1069 CDD:275381 7/24 (29%)
leucine-rich repeat 1070..1099 CDD:275381 9/31 (29%)
leucine-rich repeat 1100..1124 CDD:275381 6/24 (25%)
leucine-rich repeat 1125..1144 CDD:275381 4/18 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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