DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and jet

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	68/260 - (26%)
Similarity:	121/260 - (46%)	Gaps:	26/260 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 DTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCWHISDQGIGHLAGFSRE 340
            |..:.::|.:| :|:.|....||  :.|....:...|:|.:.|      |:|.....::....|.
  Fly    48 DVLIPQVAVYL-SLKDLFNLRCC--SRTAQRFVEAALEKRQEL------HLSGNNTKNIDVAFRV 103

  Fly   341 TAEGNLQLEYLGLQDCQRLSDE-ALGHIAQGLTSLKSINLSFCVSVTDSGLKH-LARMPKLEQLN 403
            .|....:||.|.|..|:.|:|| .|..:|.....|.::||:.||::|...|:. :....:|..|.
  Fly   104 LARCCQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLK 168

  Fly   404 LRSCDNISDIGMAYLTEGGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSL-NQCQITDHGML 467
            |..|..::...:..||...|.:...|:|:|..|.::.|....:.|.:|..||| |...:||..::
  Fly   169 LSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLI 233

  Fly   468 KIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSKGIDIIMKLPKLQKLNL 532
            :|.....|||::|:..|:.|:|.|:..|......|:|:              :|.:.|::.:|:|
  Fly   234 QIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTL--------------LIRRCPRVTELSL 284

Fly 533 532
Fly 285 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689
		AMN1	<226..>334	CDD:187754	13/57 (23%)
		leucine-rich repeat	236..256	CDD:275381
		leucine-rich repeat	263..288	CDD:275381	3/11 (27%)
		leucine-rich repeat	289..314	CDD:275381	6/24 (25%)
		leucine-rich repeat	315..347	CDD:275381	5/31 (16%)
		AMN1	347..524	CDD:187754	50/179 (28%)
		leucine-rich repeat	348..373	CDD:275381	10/25 (40%)
		leucine-rich repeat	374..398	CDD:275381	7/24 (29%)
		leucine-rich repeat	399..424	CDD:275381	6/24 (25%)
		leucine-rich repeat	425..450	CDD:275381	6/24 (25%)
		leucine-rich repeat	451..475	CDD:275381	8/24 (33%)
		leucine-rich repeat	476..501	CDD:275381	8/24 (33%)
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	5/30 (17%)
		AMN1	96..>261	CDD:187754	48/164 (29%)
		leucine-rich repeat	111..137	CDD:275381	10/25 (40%)
		leucine-rich repeat	138..163	CDD:275381	7/24 (29%)
		leucine-rich repeat	164..189	CDD:275381	6/24 (25%)
		leucine-rich repeat	190..215	CDD:275381	6/24 (25%)
		leucine-rich repeat	216..241	CDD:275381	8/24 (33%)
		leucine-rich repeat	242..267	CDD:275381	8/24 (33%)
		leucine-rich repeat	268..290	CDD:275381	6/31 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740