Protein Alignment Ppa and fbxl6

DIOPT Version :9

• Sequence 1: NP_001261138.1
• Gene: Ppa / 37602
• FlyBaseID: FBgn0020257
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001296447.1
• Gene: fbxl6 / 323163
• ZFINID: ZDB-GENE-060810-162
• Length: 564
• Species: Danio rerio
• Alignment Length: 436
• Identity: 90/436 - (20%)
• Similarity: 165/436 - (37%)
• Gaps: 121/436 - (27%)

  Fly   155 ELLEQIFEHLPVRD-----LGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGI 214
            |:|.:||:....:|     |.|..:||..|..||.:..:|:.|           |:..|.::.|
Zfish   151 EILVKIFQFAVFQDGAVPLLCRVGRVCRLWNGAASSPILWRSV-----------SIGYCWIEPG- 203

  Fly   215 KKVQILSLRRSLKDLVLGVPALTSLNLSGCFNVADMNLGH----------AFSVDLPNLKTLDLS 269
             |.|:....:.:|:.|      ..|..:..|.:.:.:|.|          ..|....:|.:|.||
Zfish   204 -KSQLPGTEQKIKNTV------DWLAENRLFQLREFSLCHWKKNVDYVIQKVSQSCLSLHSLKLS 261

  Fly   270 LCKQITDTSLGRIAQHLRNLETLELGGC-CNITNTGLLLIAWG--LKKLKHLNLRSCWHISDQGI 331
            .|..:|:.:...:....::||.:.:... .|:......|.|:|  :||:...:...    ||:.:
Zfish   262 YCTGMTEKAFQNLGADCQSLEDINVQHSEINVDGLVSFLEAYGNQIKKIYFTHSTK----SDKLL 322

  Fly   332 GHLA------------------GFSRETAEGNLQLEYLGLQ-DCQRLSDEALGHIAQGLTSLKSI 377
            ..|:                  |:|:      |.:...||| .|.:|....|.::......:::|
Zfish   323 SALSKGCCPELRLLEINTKLDGGYSQ------LPICIQGLQIGCPKLQTFRLMNVTAVPKMIRNI 381

  Fly   378 NLS---------FCVS------VTDSGLKH-LARMPKLEQLNLRSCDNISDIGMAYL-------- 418
            ..|         .|::      :||:.|.: |...|.|..|:||....|:..|:..|
Zfish   382 PSSTCGFPMLEELCIATSFHSFMTDNDLNNVLHGSPNLRVLDLRGGSRITPTGLYALPCERLECF 446

  Fly   419 ----------------------TEGGSGINSLDVS---FCDKISDQALTHIAQ--GLYRLRSLSL 456
                                  .:..:.:..||::   |.::..:.|:.|:|.  |:...|||:|
Zfish   447 YWGLYFNSNTMVASKKGIHMLAQKWSNTLRELDLANQPFSEEDLEIAMGHLAHSVGVEFFRSLNL 511

  Fly   457 NQCQITDHGMLKIAKALHELENLNIGQCSRITDKGLQTL---AEDL 499
            :..:||...:..:......|:.||:..| |...:||:.|   .||:
Zfish   512 SGTKITSSALRLLINQAPALKYLNLSSC-RYLPRGLKRLYHGQEDI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	12/39 (31%)
		AMN1	<226..>334	CDD:187754	23/120 (19%)
		leucine-rich repeat	236..256	CDD:275381	4/29 (14%)
		leucine-rich repeat	263..288	CDD:275381	6/24 (25%)
		leucine-rich repeat	289..314	CDD:275381	6/27 (22%)
		leucine-rich repeat	315..347	CDD:275381	5/49 (10%)
		AMN1	347..524	CDD:187754	44/208 (21%)
		leucine-rich repeat	348..373	CDD:275381	6/25 (24%)
		leucine-rich repeat	374..398	CDD:275381	7/39 (18%)
		leucine-rich repeat	399..424	CDD:275381	7/54 (13%)
		leucine-rich repeat	425..450	CDD:275381	7/29 (24%)
		leucine-rich repeat	451..475	CDD:275381	6/23 (26%)
		leucine-rich repeat	476..501	CDD:275381	10/27 (37%)
fbxl6	NP_001296447.1	F-box-like	147..195	CDD:289689	14/54 (26%)
		AMN1	213..396	CDD:187754	35/198 (18%)
		leucine-rich repeat	229..254	CDD:275381	3/24 (13%)
		leucine-rich repeat	255..280	CDD:275381	6/24 (25%)
		leucine-rich repeat	281..306	CDD:275381	6/24 (25%)
		leucine-rich repeat	307..334	CDD:275381	5/30 (17%)
		leucine-rich repeat	335..362	CDD:275381	7/32 (22%)
		AMN1	<391..>542	CDD:187754	31/151 (21%)
		leucine-rich repeat	391..418	CDD:275381	5/26 (19%)
		leucine-rich repeat	419..438	CDD:275381	6/18 (33%)
		leucine-rich repeat	445..473	CDD:275381	0/27 (0%)
		leucine-rich repeat	475..505	CDD:275381	7/29 (24%)
		leucine-rich repeat	506..530	CDD:275381	6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810