DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ppa and Fbxo33

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:XP_006240181.1 Gene:Fbxo33 / 314157 RGDID:1307543 Length:563 Species:Rattus norvegicus


Alignment Length:442 Identity:98/442 - (22%)
Similarity:146/442 - (33%) Gaps:141/442 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 SNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGVEAKLHLKRSSPSLFNCLVKRGI 214
            ::|..||:..||..||..|..||:..|:.||:..:..::|             |.|..||.....
  Rat    72 ASLPSELIVHIFSFLPAPDRLRASASCSHWRECLFYPALW-------------PQLRICLRVSPA 123

  Fly   215 KKVQILSLRRSLKDLV--LGVPALTSLNLSGCFNVADMNLGHAFSVDLPN--------------- 262
            ::.::..|.|.....|  |.|.......|||.....|.. |.....|..|               
  Rat   124 EQPRLEFLMRKCGWFVRELRVEFAAENYLSGGGGPGDGG-GSGGGTDTGNGGEESEALQLSSRWL 187

  Fly   263 --LKT-LDLSLCKQITDTSLGRIAQHLRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSCW 324
              |:. |:|.||..::       .::.|||:...|.|..::                        
  Rat   188 EVLRIYLELVLCVLLS-------IRNNRNLQKFSLFGDISV------------------------ 221

  Fly   325 HISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVS-VTDS 388
             :..||.......||...:|.      .::..|:|.:|.|.:..|    ||.::..|.:. ||.|
  Rat   222 -VQQQGSLSSTYLSRVDPDGK------KIKQIQQLFEEILSNSRQ----LKWLSCGFMLEIVTPS 275

  Fly   389 GLKHLAR--MPKLEQLNLRSCDNI---SDIGMAYLTEGGSGINSLDVSFCDKISDQA-------- 440
            .|..|:.  ...:|.|:|.. :||   |.:..|...|....:.||.:.|||..::.|        
  Rat   276 SLSSLSNSIANTMEHLSLLD-NNIPGNSTLITAVELERFVNLRSLALDFCDFTAEMARVLTDSNH 339

  Fly   441 --------LTHIAQGLYRLRSLS---------------------LNQCQITDHGMLKIAKALHEL 476
                    |.|.|..:  |:||.                     |....:....||||.|....|
  Rat   340 VPLQRLSLLVHNASVM--LKSLDNMPNDEHWKALSRKSSSLRVYLMAFDVKSEDMLKILKPSIPL 402

  Fly   477 ENLN------------IGQCSRITDKGLQ--TLAEDLTNLKTIDLYGCTQLS 514
            |.::            :...||..||.|.  .|..|:     ||..|...||
  Rat   403 ERVHFDSYVTCVSGAIVDLISRQYDKFLTHFILMNDM-----IDTSGFPDLS 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689 13/39 (33%)
AMN1 <226..>334 CDD:187754 22/127 (17%)
leucine-rich repeat 236..256 CDD:275381 5/19 (26%)
leucine-rich repeat 263..288 CDD:275381 5/25 (20%)
leucine-rich repeat 289..314 CDD:275381 3/24 (13%)
leucine-rich repeat 315..347 CDD:275381 5/31 (16%)
AMN1 347..524 CDD:187754 53/225 (24%)
leucine-rich repeat 348..373 CDD:275381 5/24 (21%)
leucine-rich repeat 374..398 CDD:275381 8/26 (31%)
leucine-rich repeat 399..424 CDD:275381 8/27 (30%)
leucine-rich repeat 425..450 CDD:275381 9/40 (23%)
leucine-rich repeat 451..475 CDD:275381 9/44 (20%)
leucine-rich repeat 476..501 CDD:275381 9/38 (24%)
Fbxo33XP_006240181.1 F-box-like 72..119 CDD:289689 17/59 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.