DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppa and Fbxl15

DIOPT Version :9

Sequence 1:NP_001261138.1 Gene:Ppa / 37602 FlyBaseID:FBgn0020257 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_001101073.1 Gene:Fbxl15 / 309453 RGDID:1306444 Length:300 Species:Rattus norvegicus


Alignment Length:259 Identity:71/259 - (27%)
Similarity:121/259 - (46%) Gaps:47/259 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   286 LRNLETLELGGCCNITNTGLLLIAWGLKKLKHLNLRSC--WHISDQGIGHLAGFSRETAEGNLQL 348
            ||..:..::|.  .|....|:.:....:.|:.|.|..|  |.:.:..:..||        .|.||
  Rat    62 LRRFDAAQVGP--QIPRAALVRLLRDAEGLQELALAPCHEWLLDEDLVPVLA--------RNPQL 116

  Fly   349 EYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVSVTDSGLKHLA-RMPKLEQLNLRSCDNISD 412
            ..:.|..|.:||..|||.:|:|...|:.|:|:.|..|....|:.|| |.|.||:|:|.:|..:.|
  Rat   117 RSVALAGCGQLSRRALGALAEGCPRLQRISLAHCDWVDGLALRGLADRCPALEELDLTACRQLKD 181

  Fly   413 IGMAYLTE-GGSGINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQITDHGMLKIAKALHEL 476
            ..:.||.: .|:|:.||                        ||::| ..:.|..:.::|:...:|
  Rat   182 EAIVYLAQRRGAGLRSL------------------------SLAVN-ANVGDTAVQELARNCPQL 221

  Fly   477 ENLNIGQCSRITDKGLQTLAEDLTNLKTIDLYGC--------TQLSSKGIDIIMKLPKLQKLNL 532
            |:|::..|.|:...|::||||....|:::.:..|        ::|..:|:||.::.|..|.|.|
  Rat   222 EHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVL 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpaNP_001261138.1 F-box-like 149..190 CDD:289689
AMN1 <226..>334 CDD:187754 10/49 (20%)
leucine-rich repeat 236..256 CDD:275381
leucine-rich repeat 263..288 CDD:275381 1/1 (100%)
leucine-rich repeat 289..314 CDD:275381 3/24 (13%)
leucine-rich repeat 315..347 CDD:275381 8/33 (24%)
AMN1 347..524 CDD:187754 54/186 (29%)
leucine-rich repeat 348..373 CDD:275381 10/24 (42%)
leucine-rich repeat 374..398 CDD:275381 9/24 (38%)
leucine-rich repeat 399..424 CDD:275381 9/25 (36%)
leucine-rich repeat 425..450 CDD:275381 2/24 (8%)
leucine-rich repeat 451..475 CDD:275381 5/23 (22%)
leucine-rich repeat 476..501 CDD:275381 10/24 (42%)
Fbxl15NP_001101073.1 F-box 18..55 CDD:395521
leucine-rich repeat 62..88 CDD:275381 5/27 (19%)
leucine-rich repeat 89..115 CDD:275381 8/33 (24%)
Interaction with SMURF1. /evidence=ECO:0000250 113..269 52/180 (29%)
leucine-rich repeat 116..141 CDD:275381 10/24 (42%)
AMN1 <139..>268 CDD:187754 40/153 (26%)
leucine-rich repeat 142..167 CDD:275381 9/24 (38%)
leucine-rich repeat 168..194 CDD:275381 9/25 (36%)
leucine-rich repeat 195..220 CDD:275381 7/49 (14%)
leucine-rich repeat 221..245 CDD:275381 10/23 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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